Novel antiviral effect of lithium chloride on mammalian orthoreoviruses in vitro

文献类型: 外文期刊

第一作者: Chen, Ye

作者: Chen, Ye;Cai, Gengyuan;Jiang, Zhiguo;Jiao, Yiren;Shi, Yuzhen;Li, Huaqin;Wang, Chong;Kong, Deyang

作者机构:

关键词: LiCl;Reovirus;Antiviral effect;Replication

期刊名称:MICROBIAL PATHOGENESIS ( 影响因子:3.738; 五年影响因子:3.663 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: Reovirus not only causes considerable economic loss in the swine industry of the United States and other countries, but also threatens the public health due to its zoonotic potential. According to previous reports, LiCl has antiviral activity against a number of viruses. The inhibitory effects of LiCl on reovirus life cycle in Vero cells were evaluated. The unpaired t-test and one-way ANOVA were used to analyze the differences between experimental groups. We first found that LiCl treatment significantly inhibited reovirus replication in a dose-dependent manner. Furthermore, we found that this antiviral activity of LiCl targets the early stage of viral replication. LiCl could be a potential drug against reovirus infection. (C) 2016 Elsevier Ltd. All rights reserved.

分类号: R3

  • 相关文献

[1]Lithium chloride inhibits early stages of foot-and-mouth disease virus (FMDV) replication in vitro. Zhao, Fu-Rong,Xie, Yin-Li,Liu, Ze-Zhong,Shao, Jun-Jun,Li, Shi-Fang,Zhang, Yong-Guang,Chang, Hui-Yun,Zhao, Fu-Rong,Xie, Yin-Li,Liu, Ze-Zhong,Shao, Jun-Jun,Li, Shi-Fang,Zhang, Yong-Guang,Chang, Hui-Yun,Zhao, Fu-Rong. 2017

[2]PI3K/Akt/p53 pathway inhibits reovirus infection. Zhang, Xiaozhan,Wu, Hongxia,Liu, Chunguo,Tian, Jin,Qu, Liandong.

[3]In vitro protective efficacy of Lithium chloride against Mycoplasma hyopneumoniae infection. Ishag, Hassan Z. A.,Wu, Yu-zi,Liu, Mao-jun,Xiong, Qi-yan,Feng, Zhi-xin,Yang, Ruo-song,Shao, Guo-qing,Ishag, Hassan Z. A..

[4]Multiple microRNAs targeted to internal ribosome entry site against foot-and-mouth disease virus infection in vitro and in vivo. Chang, Yanyan,Dou, Yongxi,Bao, Huifang,Luo, Xuenong,Liu, Xuerong,Mu, Kebin,Liu, Zaixin,Liu, Xiangtao,Cai, Xuepeng,Chang, Yanyan,Liu, Xuerong,Mu, Kebin,Cai, Xuepeng. 2014

[5]Molecular cloning and characterizations of porcine SAMHD1 and its roles in replication of highly pathogenic porcine reproductive and respiratory syndrome virus. Yang, Shen,Shan, Tongling,Zhou, Yanjun,Jiang, Yifeng,Tong, Wu,Liu, Fei,Wen, Feng,Zhang, Qingzhan,Tong, Guangzhi,Shan, Tongling,Zhou, Yanjun,Tong, Guangzhi.

[6]Reovirus infection emerged in cultured channel catfish, Ictalurus punctatus, in China. Zeng, Lingbing,Luo, Xiaosong,Fan, Yuding,Xu, Jin,Wang, Yao,Gong, Shiyuan. 2013

[7]Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes. Tian, Jin,Zhang, Xiaozhan,Wu, Hongxia,Liu, Chunguo,Li, Zhijie,Hu, Xiaoliang,Qu, Liandong,Su, Shuo,Wang, Lin-Fa. 2015

[8]A potentially novel reovirus isolated from swine in northeastern China in 2007. Zhang, Chaofan,Liu, Shanshan,Lin, Wencheng,Hu, Feng,Cui, Shangjin,Liu, Licheng,Wang, Pengzhi,Chen, Weijun,Wu, Weili,Chen, Weijun. 2011

[9]Mycoreovirus genome alterations: similarities to and differences from rearrangements reported for other reoviruses. Tanaka, Toru,Eusebio-Cope, Ana,Suzuki, Nobuhiro,Sun, Liying. 2012

[10]Mycoreovirus 1 S4-coded protein is dispensable for viral replication but necessary for efficient vertical transmission and normal symptom induction. Eusebio-Cope, Ana,Suzuki, Nobuhiro,Sun, Liying,Hillman, Bradley I.. 2010

[11]BIRC7 gene in channel catfish (Ictalurus punctatus): Identification and expression analysis in response to Edwardsiella tarda, Streptococcus iniae and channel catfish Hemorrhage Reovirus. Li, Min,Wang, Qi-Long,Chen, Song-Lin,Sha, Zhen-Xia,Li, Min,Liu, Yang.

[12]Isolation and characterization of a reovirus causing spleen necrosis in Pekin ducklings. Liu, Qinfang,Zhang, Guozhong,Ren, Gaixian,Chen, Liben,Gao, Jian,Zhang, Dabing,Han, Bo,Su, Wenliang,Zhao, Jixun,Su, Jingliang,Hu, Xueying,Huang, Yu.

[13]Complete genomic sequence of a reovirus isolated from grass carp in China. Ye, Xing,Tian, Yuan-yuan,Deng, Guo-cheng,Chi, Yan-yan,Jiang, Xiao-yan,Chi, Yan-yan.

[14]The Complete Genome Sequence of Two Isolates of Southern rice black-streaked dwarf virus, a New Member of the Genus Fijivirus. Wang, Qiang,Zhou, Guo-Hui,Yang, Jian,Zhang, Heng-Mu,Chen, Jian-Ping,Adams, Michael J..

[15]Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity. Leung, Bo Wah,Brownlee, George G.,Chen, Hualan. 2010

[16]C-terminal region of apoptin affects chicken anemia virus replication and virulence. Wang, Yongqiang,Hu, Yonghao,Chen, Hualan,Wang, Yongqiang,Song, Xiuqing,Gao, Honglei,Wang, Xiaoyan,Gao, Yulong,Qi, Xiaole,Qin, Liting,Lin, Huan,Gao, Li,Yao, Shuai,Han, Chunyan,Wang, Xiaomei,Chen, Hualan. 2017

[17]Porcine 2 ', 5 '-oligoadenylate synthetase 2 inhibits porcine reproductive and respiratory syndrome virus replication in vitro. Zhao, Mengmeng,Wan, Bo,He, Jian,Zhang, Gaiping,Li, Huawei,Chen, Xinxin,Wang, Linjian,Wang, Yinbiao,Xie, Sha,Qiao, Songlin,Zhang, Gaiping,Zhang, Gaiping. 2017

[18]The ecdysteroid UDP-glucosyltransferase gene promoter from Autographa californica multicapsid nucleopolyhedrovirus. Shen, XJ,Yi, YZ,Tang, SM,Zhang, ZF,Li, YR,He, JL.

[19]Establishment of a novel and highly permissive cell line for the efficient replication of cyprinid herpesvirus 2 (CyHV-2). Ma, Jie,Jiang, Nan,Xu, Jin,Fan, Yuding,Zhou, Yong,Zeng, Lingbing,LaPatra, Scott E.,Jin, Ling.

[20]Newcastle disease virus induces stable formation of bona fide stress granules to facilitate viral replication through manipulating host protein translation. Sun, Yingjie,Dong, Luna,Yu, Shengqing,Wang, Xiaoxu,Zheng, Hang,Zhang, Pin,Meng, Chunchun,Zhan, Yuan,Tan, Lei,Song, Cuiping,Qiu, Xusheng,Liao, Ying,Ding, Chan,Dong, Luna,Zheng, Hang,Wang, Xiaoxu,Wang, Guijun,Ding, Chan.

作者其他论文 更多>>