Stereoselective induction by 2,2 ',3,4 ',6-pentachlorobiphenyl in adult zebrafish (Danio rerio): Implication of chirality in oxidative stress and bioaccumulation

文献类型: 外文期刊

第一作者: Chai, Tingting

作者: Chai, Tingting;Cui, Feng;Mu, Xiyan;Yang, Yang;Qi, Suzhen;Zhu, Lizhen;Wang, Chengju;Chai, Tingting;Qiu, Jing

作者机构:

关键词: PCB91;Zebrafish;Oxidative stress;Bioconcentration

期刊名称:ENVIRONMENTAL POLLUTION ( 影响因子:8.071; 五年影响因子:8.35 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: This study aimed to investigate the oxidative stress process and bioaccumulation the racemic/(-)-/(+)-2,2',3,4',6-pentachlorobiphenyl were administered to adult zebrafish (Danio redo) after prolonged exposure of 56-days uptake and 49-days depuration experiments. Stereoselective accumulation was observed in adult samples after racemic exposure as revealed by decreased enantiomer fractions. The two enantiomers of PCB91 accumulated at different rates with logBCF(k) values close to 3.7, suggesting that they were highly hazardous and persistent pollutants. Exposure to racemic/(-)-/(+)- PCB91 stereo selectively induced oxidative stress owing to changes in reactive oxygen species, malondialdehyde contents, antioxidant enzyme activities and gene expressions in brain and liver tissues. In addition, the stereoselective relationship between bioconcentration and oxidative stress were also presented in this study. Our findings might be helpful for elucidating the environmental risk of the two enantiomers of PCB91 that induce toxicity in aquatic organisms. (C) 2016 Elsevier Ltd. All rights reserved.

分类号: X5

  • 相关文献

[1]Acute toxicity, bioconcentration, elimination and antioxidant effects of fluralaner in zebrafish, Danio rerio. Jia, Zhong-Qiang,Liu, Di,Sheng, Cheng-Wang,Chen, Yu-Ming,Han, Zhao-Jun,Zhao, Chun-Qing,Casida, John E.,Wang, Chen,Song, Ping-Ping. 2018

[2]The enantioselective toxicity and oxidative stress of beta-cypermethrin on zebrafish. Mu, Xiyan,Shen, Gongming,Huang, Ying,Luo, Jianbo,Li, Yingren,Zhu, Lizhen,Wang, Chengju,Li, Xuefeng,Qi, Suzhen.

[3]Pretilachlor has the potential to induce endocrine disruption, oxidative stress, apoptosis and immunotoxicity during zebrafish embryo development. Jiang, Jinhua,Chen, Yanhong,Yu, Ruixian,Zhao, Xueping,Wang, Qiang,Cai, Leiming. 2016

[4]Effect of acetochlor on transcription of genes associated with oxidative stress, apoptosis, immunotoxicity and endocrine disruption in the early life stage of zebrafish. Jiang, Jinhua,Wu, Shenggan,Liu, Xinju,Wang, Yanhua,An, Xuehua,Cai, Leiming,Zhao, Xueping.

[5]Mercury in Sclerotia of Wolfiporia Extensa (Peck) Ginns Fungus Collected Across of the Yunnan Land. Wiejak, Anna,Falandysz, Jerzy,Wang Yuan-zhong,Zhang Ji. 2016

[6]Accumulation and Tolerance Characteristics of Zinc in Agropyron cristatum Plants Exposed to Zinc-Contaminated Soil. Meng, Lin,Guo, Qiang,Mao, Peichun,Tian, Xiaoxia. 2013

[7]Liquid chromatography-mass spectrometry method for evaluating the dissipation dynamics of cyromazine and its metabolite in Agaricus bisporus and dietary risk assessment. Zhao, Zhiyong,Chen, Lei,Bai, Bing,Yang, Xianli,Wang, Jianhua,Zhao, Xiaoyan,Zhou, Changyan,Tan, Yanglan. 2018

[8]The integration of in vivo and in vitro metabolism assays to investigate the stereoselective behaviors of benalaxyl in rainbow trout (Oncorhynchus mykiss). Gu, Xu,Gu, Xu,Yao, Ting. 2013

[9]Arsenic Concentrations and Associated Health Risks in Laccaria Mushrooms from Yunnan (SW China). Zhang, Ji,Wang, Yuan-Zhong,Li, Tao,Yang, Ya-Li,Liu, Hong-Gao.

[10]Bioconcentration potential and contamination with mercury of pantropical mushroom Macrocybe gigantea. Wiejak, Anna,Falandysz, Jerzy,Wang, Yuanzhong,Zhang, Ji.

[11]Uptake and translocation of imidacloprid, thiamethoxam and difenoconazole in rice plants. Ge, Jing,Yan, Huangqian,Li, Yong,Chai, Yangyang,Liu, Xianjin,Yu, Xiangyang,Cui, Kai,Cheng, Jiangfeng,Ge, Jing,Li, Yong,Chai, Yangyang,Yu, Xiangyang.

[12]Effects of the bioconcentration and parental transfer of environmentally relevant concentrations of difenoconazole on endocrine disruption in zebrafish (Danio rerio). Teng, Miaomiao,Zhu, Wentao,Wang, Yao,Wang, Dezhen,Wang, Chengju,Qi, Suzhen,Dong, Kai. 2018

[13]CS5931, a Novel Polypeptide in Ciona savignyi, Represses Angiogenesis via Inhibiting Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases (MMPs). Liu, Ge,Wu, Ning,Liu, Ge,Liu, Ming,Wei, Jianteng,Huang, Haijuan,Zhang, Yuyan,Zhao, Jin,Xiao, Lin,Zheng, Lanhong,Lin, Xiukun. 2014

[14]Proteomic profile and toxicity pathway analysis in zebrafish embryos exposed to bisphenol A and di-n-butyl phthalate at environmentally relevant levels. Dong, Xing,Qiu, Xuchun,Xu, Hai,Wu, Xiangyang,Qiu, Xuchun,Meng, Shunlong,Yang, Ming. 2018

[15]Identification of a virulence-related surface protein XF in piscine Streptococcus agalactiae by pre-absorbed immunoproteomics. Liu, Guangjin,Zhang, Wei,Liu, Yongjie,Yao, Huochun,Lu, Chengping,Xu, Pao. 2014

[16]Cloning, characterization and expression analysis of interleukin-10 from the zebrarish (Danio rerion). Zhang, DC,Shao, YQ,Huang, YQ,Jiang, SG. 2005

[17]Generation of Tg(cyp1a:gfp) Transgenic Zebrafish for Development of a Convenient and Sensitive In Vivo Assay for Aryl Hydrocarbon Receptor Activity. Xu, Hongyan,Li, Caixia,Li, Yan,Ng, Grace Hwee Boon,Liu, Chunsheng,Zhang, Xiaoyan,Gong, Zhiyuan,Xu, Hongyan,Liu, Chunsheng.

[18]The role of apoptosis in MCLR-induced developmental toxicity in zebrafish embryos. Zeng, Cheng,Wang, Jianghua,Zhang, Guirong,Chen, Nan,Li, Guangyu,Sun, Hong,Xie, Ping,Li, Guangyu,Yan, Wei. 2014

[19]Dexamethasone-induced hepatomegaly and steatosis in larval zebrafish. Yin, Guojun,Kitazawa, Takio,Teraoka, Hiroki,Yin, Guojun,Cao, Liping,Du, Jinliang,Jia, Rui,Kubota, Akira.

[20]Stereoselective Determination of Tebuconazole in Water and Zebrafish by Supercritical Fluid Chromatography Tandem Mass Spectrometry. Liu, Na,Dong, Fengshou,Xu, Jun,Liu, Xingang,Chen, Zenglong,Tao, Yan,Pan, Xinglu,Chen, XiXi,Zheng, Yongquan.

作者其他论文 更多>>