The pathogenicity of novel duck reovirus in Cherry Valley ducks

文献类型： 外文期刊

第一作者： Li, Ning

作者： Li, Ning;Hong, Tianqi;Wang, Yao;Cai, Yumei;Liu, Sidang;Wei, Liangmeng;Chai, Tongjie;Li, Ning;Wei, Liangmeng;Chai, Tongjie;Wang, Youling;Yu, Kexiang

作者机构：

关键词： Novel duck reovirus;Pathogenicity Innate immunity;Cherry;Valley duck

期刊名称：VETERINARY MICROBIOLOGY （ 影响因子：3.293； 五年影响因子：3.599 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： The novel duck reovirus (NDRV) is an emerging, contagious infection. To better realize the pathogenic mechanism of NDRV in ducks, an infection experiment was conducted. The resulting data demonstrated that typical gross lesions were observed in the infected ducks. NDRV was able to replicate in various tissues, leading to these pathological lesions, especially on the liver and spleen. Real-time quantitative PCR showed that the expression of most innate immune-related genes was up-regulated and the antiviral innate immune response could be established in both the liver and spleen. This study indicates that NDRV is a pantropic virus. To resist viral infection, several pathogen recognition receptors can cooperatively recognize NDRV and initiate innate immunity, but the responses are different between different tissues. As far as we know, this is the first systematic investigation of the pathogenicity of NDRV in Cherry Valley ducks based on the host's innate immunity, and these data will provide new insights into the further study of the disease. (C) 2016 Elsevier B.V. All rights reserved.

分类号： S8

  • 相关文献

[1]Comparative Study of Phenolic Compounds and Antioxidant Activity in Different Species of Cherries. Liu, Yun,Zhong, Fei,Tian, Rongrong,Li, Tianhong,Liu, Xinyan,Zhang, Kaichun,Zhang, Xiaoming. 2011

[2]Phloem-specific expression of beta-glucuronidase (GUS) driven by a heterologous AtSUC2 promoter in transgenic cherries. Liu Qing-zhong,Xin, Chen,Zhao Hong-jun,Yan, Zhao,Hammond, R. W.,Davis, R. E.. 2016

[3]Protective immune responses in ducklings induced by a suicidal DNA vaccine of the sigma C gene of novel duck reovirus. Zhu, Yingqi,Li, Chuanfeng,Bi, Zhuangli,Chen, Zongyan,Meng, Chunchun,Ding, Chan,Liu, Guangqing,Zhu, Yingqi,Bi, Zhuangli,Wang, Gui-Jun.

[4]Reference gene selection for quantitative real-time PCR normalization in different cherry genotypes, developmental stages and organs. Ye, Xia,Zhang, Fangming,Tao, Yonghuan,Song, Shangwei,Fang, Jinbao.

[5]MOLECULAR CHARACTERIZATION OF THE sigma C-ENCODING GENE FROM NOVEL DUCK REOVIRUS. Yun, T.,Hua, J.,Yu, B.,Chen, L.,Ni, Z.,Ye, W.,Zhang, C.,Chen, H.. 2015

作者其他论文 更多>>

微信小程序