A facile one-step folic acid modified partially oxidized graphene for high sensitivity tumor cell sensing
文献类型： 外文期刊
第一作者： Gao, Wenyu
作者： Gao, Wenyu;Zheng, Qing;Shen, Zongxu;Wu, Hao;Wu, Songmei;Yu, Yu;Ding, Kejian;Zheng, Qing;Ma, Yuehui;Guan, Weijun
作者机构：
期刊名称：ANALYST （ 影响因子：4.616； 五年影响因子：4.232 ）
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年卷期：
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收录情况： SCI
摘要： A highly sensitive and selective tumor cell sensor based on partially oxidized graphene (POG) and folate acid (FA) composite was constructed. The POG was prepared through a modified Hummers method and characterized by means of Raman spectroscopy, X-ray photoelectron spectroscopy, cyclic voltammetry, atomic force microscopy and transmission electron microscopy. The as-prepared POG exhibited the advantages of high electrochemical activity and a good capacity of linking amine derivatives. Using a facile one step reaction, the FA-modified POG was endowed with a more sensitive response to folate-expressing tumor cells than those sensors constructed by the two-step reaction, as well as high selectivity, good reproducibility and long-term stability.
分类号： O65
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