Role of the ubiquitin-proteasome pathway on proteolytic activity in postmortem proteolysis and tenderisation of sheep skeletal muscle

文献类型: 外文期刊

第一作者: Liu, Yue

作者: Liu, Yue;Du, Manting;Li, Xin;Chen, Li;Zhang, Dequan;Liu, Yue;Tian, Jianwen;Shen, Qingwu

作者机构:

关键词: Proteasome;sheep;skeletal muscle;tenderisation;ubiquitin

期刊名称:INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY ( 影响因子:3.713; 五年影响因子:3.408 )

ISSN:

年卷期:

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收录情况: SCI

摘要: The objective of this study was to investigate the effects of ubiquitin-proteasome pathway on meat tenderisation. The sheep muscle longissimus lumborum was injected with or without PYR-41 (inhibitor of ubiquitination) or MG-132 (inhibitor of proteasome). Muscle samples were collected at 6, 15, 24 and 48h after injection. Myofibrillar protein degradation, muscle ultrastructure and sarcomere length were determined. Results showed that inhibition of proteasome or ubiquitination affected sarcomere length at 48h after treatments. Destruction of muscle ultrastructure in both treatments was reduced when compared to control. Inhibition of proteasome produced different fragments of myofibrillar proteins in comparison with control at 48h. In conclusion, ubiquitin-proteasome plays a role in postmortem proteolysis and might contribute to meat tenderisation.

分类号: TS2

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