Dietary litchi pulp polysaccharides could enhance immunomodulatory and antioxidant effects in mice

文献类型： 外文期刊

第一作者： Huang, Fei

作者： Huang, Fei;Zhang, Ruifen;Liu, Yang;Xiao, Juan;Liu, Lei;Wei, Zhencheng;Zhang, Mingwei;Liu, Dong;Yi, Yang

作者机构：

关键词： Litchi pulp polysaccharides;Immunomodulatory activity;Antioxidant activity

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：6.953； 五年影响因子：6.737 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： The purpose of this study was, to investigate the immunomodulatory and antioxidant activities of litchi pulp polysaccharides (LP) in cyclophosphamide (Cy)-induced mice. The administration of LP (50, 100 and 200 mg/kg/d) remarkably enhanced mesenteric lymph node cells proliferation and serum IgA. Moreover, IL-6, TNF-alpha, IgG and IgM levels in serum were significantly improved in a dose-dependent manner with LP treatment. Dietary LP induced systemic immune responses including stimulating the proliferation of splenocytes, balancing the ratio of spleen lymphocyte subsets, up-regulating the thymus and spleen indices. Thus, we speculate litchi polysaccharides would express their systemic immunomodulatory effects by triggering the intestinal mucosal immunity. Likewise, LP also significantly increased total antioxidant capacity, as well as superoxidase dismutase and glutathione peroxidase activity, while decreasing malondialdehyde levels in the serum and liver. The immunomodulatory activity of LP was accompanied with its antioxidant activity, which might be related with its structure and prebiotic effect. This is a novel study on the relationship between the immunomodulatory and antioxidant activities of litchi polysaccharides. (C) 2016 Published by Elsevier B.V.

分类号： Q71

  • 相关文献

[1]Characterization, antioxidant activity and immunomodulatory activity of polysaccharides from the swollen culms of Zizania latifolia. Wang, Mingchun,Zhu, Peilei,Zhao, Shiwei,Nie, Chenzhipeng,Wang, Naifu,Du, Xianfeng,Zhou, Yibin,Wang, Mingchun,Zhao, Shiwei,Nie, Chenzhipeng,Wang, Naifu,Du, Xianfeng,Zhou, Yibin,Wang, Mingchun,Zhu, Peilei.

[2]Purification, characterization and immunomodulatory activity of water extractable polysaccharides from the swollen culms of Zizania latifolia. Wang, Mingchun,Zhao, Shiwei,Zhu, Peilei,Nie, Chenzhipeng,Ma, Shuping,Wang, Naifu,Du, Xianfeng,Zhou, Yibin,Wang, Mingchun,Zhao, Shiwei,Zhu, Peilei,Nie, Chenzhipeng,Ma, Shuping,Wang, Naifu,Du, Xianfeng,Zhou, Yibin,Zhu, Peilei. 2018

[3]Immunomodulatory activity in vitro and in vivo of polysaccharide from Potentilla anserina. Chen, Jiong-Ran,Yang, Zhi-Qiang,Yan, Zuo-Ting,Wang, Ling,Cui, Dong-An,Hu, Ting-Jun,Niu, Ting-Xian,Wang, Meng.

[4]Physicochemical Characteristics and Immunomodulatory Activities of Three Polysaccharide-Protein Complexes of Longan Pulp. Yi, Yang,Liao, Sen Tai,Zhang, Ming Wei,Zhang, Rui Fen,Deng, Yuan Yuan,Wei, Zhen Cheng,Yi, Yang,Shi, John. 2011

[5]Immunomodulatory Activity of Polysaccharide-Protein Complex of Longan (Dimocarpus longan Lour.) Pulp. Yi, Yang,Liao, Sen-Tai,Zhang, Ming-Wei,Zhang, Rui-Fen,Deng, Yuan-Yuan,Wei, Zhen-Cheng,Yi, Yang,Yang, Bao. 2011

[6]Effects of alkali dissociation on the molecular conformation and immunomodulatory activity of longan pulp polysaccharide (LPI). Yi, Yang,Zhang, Ming-Wei,Liao, Sen-Tai,Zhang, Rui-Fen,Deng, Yuan-Yuan,Wei, Zhen-Cheng,Yi, Yang,Liao, Sen-Tai,Zhang, Rui-Fen,Deng, Yuan-Yuan,Wei, Zhen-Cheng,Yang, Bao.

[7]Structural features and immunomodulatory activities of polysaccharides of longan pulp. Yi, Yang,Zhang, Ming-Wei,Liao, Sen-Tai,Zhang, Rui-Fen,Deng, Yuan-Yuan,Wei, Zhen-Cheng,Tang, Xiao-Jun,Zhang, Yan,Yi, Yang.

[8]Chemical Composition and Immunomodulatory Activity of Mycelia of the Hairy Bracket Mushroom, Trametes hirsuta (Higher Basidiomycetes). Ma, Rongxia,Yang, Rongling,Liu, Xueming,Chen, Zhiyi,Yang, Chunying,Wang, Siyuan.

[9]Comparison of Physicochemical Properties and Immunomodulatory Activity of Polysaccharides from Fresh and Dried Litchi Pulp. Huang, Fei,Su, Dongxiao,Huang, Fei,Zhang, Ruifen,Tang, Xiaojun,Zhang, Mingwei,Su, Dongxiao,Deng, Yuanyuan,Wei, Zhencheng,Yi, Yang.

[10]Characterization and mesenteric lymph node cells-mediated immunomodulatory activity of litchi pulp polysaccharide fractions. Huang, Fei,Zhang, Ruifen,Liu, Yang,Xiao, Juan,Su, Dongxiao,Wei, Zhencheng,Zhang, Mingwei,Yi, Yang,Wang, Guangjin.

[11]Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp. Huang, Fei,Guo, Yajuan,Su, Dongxiao,Huang, Fei,Guo, Yajuan,Zhang, Ruifen,Deng, Yuanyuan,Su, Dongxiao,Zhang, Mingwei,Yi, Yang.

[12]Immunomodulatory Activity and Partial Characterisation of Polysaccharides from Momordica charantia. Deng, Yuan-Yuan,Deng, Yuan-Yuan,Yi, Yang,Zhang, Li-Fang,Zhang, Rui-Fen,Zhang, Yan,Wei, Zhen-Cheng,Tang, Xiao-Jun,Zhang, Ming-Wei,Deng, Yuan-Yuan.

[13]Antioxidant activity of alcohol aqueous extracts of Crypthecodinium cohnii and Schizochytrium sp.. Yu, Jin-hui,Sun, Jie,Wu, Ying-jie,Yu, Jin-hui,Wang, Yu,Yu, Jin-hui,Sun, Jie,Wu, Ying-jie,Yu, Jin-hui,Bian, Fei,Chen, Gao,Zhang, Yan,Bi, Yu-ping. 2017

[14]Heat Priming Induces Trans-generational Tolerance to High Temperature Stress in Wheat. Wang, Xiao,Xin, Caiyun,Cai, Jian,Zhou, Qin,Dai, Tingbo,Cao, Weixing,Jiang, Dong,Xin, Caiyun. 2016

[15]Comparison of Phenolic Content and Antioxidant Capacity of Red and Yellow Onions. Cheng, Anwei,Chen, Xiangyan,Jin, Qiong,Wang, Wenliang,Shi, John,Liu, Yaobo,Shi, John. 2013

[16]Effects of selenium and sulfur on antioxidants and physiological parameters of garlic plants during senescence. Cheng Bo,Lian Hai-feng,Yu Xin-hui,Sun Ya-li,Sun Xiu-dong,Shi Qing-hua,Liu Shi-qi,Liu Ying-ying. 2016

[17]Extraction, molecular weight distribution, and antioxidant activity of oligosaccharides from longan (Dimocarpus Longan Lour.) pulp. Lin, Xian,Chen, Jinling,Xiao, Gengsheng,Xu, Yujuan,Tang, Daobang,Wu, Jijun,Wen, Jing,Chen, Weidong. 2016

[18]Comparative Study of Phenolic Compounds and Antioxidant Activity in Different Species of Cherries. Liu, Yun,Zhong, Fei,Tian, Rongrong,Li, Tianhong,Liu, Xinyan,Zhang, Kaichun,Zhang, Xiaoming. 2011

[19]Optimized ultra-high-pressure-assisted extraction of procyanidins from lychee pericarp improves the antioxidant activity of extracts. Zhang, Ruifen,Zhang, Mingwei,Su, Dongxiao,Zhang, Ruifen,Liu, Lei,Huang, Fei,Dong, Lihong,Deng, Yuanyuan,Zhang, Yan,Wei, Zhencheng,Zhang, Mingwei,Hou, Fangli. 2017

[20]Phenolics and Antioxidant Activity of Mulberry Leaves Depend on Cultivar and Harvest Month in Southern China. Zou, Yuxiao,Sun, Yuanming,Zou, Yuxiao,Liao, Shentai,Shen, Weizhi,Liu, Fan,Tang, Cuiming,Chen, Chung-Yen Oliver. 2012

作者其他论文 更多>>

微信小程序