Deer antler: a unique model for studying mammalian organ morphogenesis

文献类型: 外文期刊

第一作者: Zhao Haiping

作者: Zhao Haiping;Chu Wenhui;Liu Zhen;Li Chunyi

作者机构:

关键词: antlerogenic periosteum;bioelectric code;pedicle periosteum;regeneration

期刊名称:ANIMAL PRODUCTION SCIENCE ( 影响因子:1.533; 五年影响因子:1.779 )

ISSN:

年卷期:

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收录情况: SCI

摘要: It is now widely accepted that organ morphogenesis in the lower animals, such as amphibians, is encoded by bioelectricity. Whether this finding applies to mammals is not known, a situation which is at least partially caused by the lack of suitable models. Deer antlers are complex mammalian organs, and their morphogenetic information resides in a primordium, the periosteum overlying the frontal crest of a prepubertal deer. The present paper reviews (1) the influence of morphogenetic information on antler formation and regeneration, and proposes that antlers are an appropriate organ for studying mammalian organ morphogenesis and (2) the storage, duplication and transferring pathways of morphogenetic information for deer antlers, and outlines a preliminary idea about how to understand the morphogenesis of mammalian organs through an involvement of bioelectricity. We believe that findings made using the deer antler model will benefit human health and wellbeing.

分类号: S`S8

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