2-(2-Phenylethyl)chromone Derivatives of Agarwood Originating from Gyrinops salicifolia

文献类型： 外文期刊

第一作者： Shao, Hang

作者： Shao, Hang;Zhu, Guo-Peng;Shao, Hang;Mei, Wen-Li;Dong, Wen-Hua;Gai, Cui-Juan;Li, Wei;Dai, Hao-Fu

作者机构：

关键词： 2-(2-phenylethyl)chromone derivative;2-(2-phenylethenyl)chromone derivative;agarwood;Gyrinops salicifolia;cytotoxicity

期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Three new 2-(2-phenylethyl)chromone derivatives (1-3) and a new 2-(2-phenylethenyl)chromone derivative (4), together with two known 2-(2-phenylethyl)chromone derivatives (5-6), were isolated from agarwood originating from Gyrinops salicifolia Ridl. The structures of compounds 1-4 were elucidated by comprehensive spectroscopic techniques (UV, IR, 1D and 2D-NMR) and MS analysis, as well as by comparison with the literature. Compounds 1, 2, and 5 showed moderate cytotoxicity against human tumor K562, BEL-7402, and SGC-7901 cell lines with IC50 values of 5.76 to 20.1 mu M.

分类号： O62

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