Microwave Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-triazolo[4,3-a]pyridine Moiety
文献类型: 外文期刊
第一作者: Zhai, Zhi-Wen
作者: Zhai, Zhi-Wen;Yang, Ming-Yan;Zhao, Wen;Sun, Zhao-Hui;Weng, Jian-Quan;Tan, Cheng-Xia;Liu, Xing-Hai;Shi, Yan-Xia;Li, Bao-Ju;Zhang, Yong-Gang
作者机构:
关键词: 1;2;4-triazolo[4;3-a]pyridine;antifungal activities;microwave assisted synthesis;thioether
期刊名称:LETTERS IN DRUG DESIGN & DISCOVERY ( 影响因子:1.15; 五年影响因子:0.994 )
ISSN:
年卷期:
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收录情况: SCI
摘要: A novel series of novel 1,2,4-triazolo[4,3-a]pyridines were designed and synthesized under microwave irradiation condition. The structures were identified by H-1 NMR, MS and elemental analysis, and the antifungal activities of them were evaluated at 100 ppm. It was found that some of the 1,2,4-triazolo[4,3-a] pyridines displayed good antifungal activity. Among them, compound 2e exhibited good antifungal activity against Stemphylium lycopersici (Enjoji) Yamamoto and Fusarium oxysporum. Sp. Cucumebrium.
分类号: R93
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