Two New Clerodane Diterpenes from Tinospora sagittata

文献类型： 外文期刊

第一作者： Ding, Wenbing

作者： Ding, Wenbing;Wan, Fanghao;Li, Youzhi;Ding, Wenbing;Li, Youzhi;Wan, Fanghao

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关键词： Tinospora sagittata;clerodane diterpenes;alpha-glucosidase inhibitory activity

期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）

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收录情况： SCI

摘要： Two new clerodane-type diterpenes, tinosporins C (1) and tinosporins D (2) were isolated from the stems of Tinospora sagittata (Oliv.), together with three known ones, columbin (3), tinophylloloside (4), and tinospinoside D (5). The structures of these compounds were determined on the basis of spectroscopic data interpretation, with that of the absolute configuration of compound 1 was assigned by experimental and calculated ECD spectra. The cytotoxicity and -glucosidase inhibitory activities of isolated compounds were evaluated in vitro.

分类号： O62

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