Structural characterization and immuno-enhancing activity of a highly branched water-soluble beta-glucan from the spores of Ganoderma lucidum
文献类型: 外文期刊
第一作者: Wang, Yatao
作者: Wang, Yatao;Liu, Yanfang;Zhou, Shuai;Zhang, Zhong;Wu, Di;Yan, Mengqiu;Tang, Qingjiu;Zhang, Jingsong;Wang, Yatao;Yan, Mengqiu;Yu, Huazheng
作者机构:
关键词: Ganoderma lucidum;Spores;beta-glucan;Structure;Immunological activity
期刊名称:CARBOHYDRATE POLYMERS ( 影响因子:9.381; 五年影响因子:8.678 )
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年卷期:
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收录情况: SCI
摘要: A water soluble beta-glucan (GLSWA-I) with a weight average molecular weight similar to 1.57 x 10(5) g/mol, isolated from the aqueous extract of the broken cellular wall Ganoderma lucidum spores, was purified by anion exchange and gel-permeation chromatography. The immunological activity test in vivo showed that GLSWA-I could significantly promote dinitrochlorobenzene (DNCB) induced delayed-type ear swelling in mice. Based on the monosaccharides composition analysis, methylation analysis, IR, 1D and 2D NMR spectroscopy, the repeating unit of polysaccharide GLSWA-I was elucidated as follows:
分类号: O629`Q53
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