Phragmalin-type limonoids from the roots of Trichilia sinensis

文献类型： 外文期刊

第一作者： Liu, Shou-Bai

作者： Liu, Shou-Bai;Chen, Hui-Qin;Guo, Zhi-Kai;Dong, Wen-Hua;Wang, Jun;Mei, Wen-Li;Dai, Hao-Fu

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期刊名称：RSC ADVANCES （ 影响因子：3.361； 五年影响因子：3.39 ）

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收录情况： SCI

摘要： Twelve new phragmalin-type limonoids, including trichisintons A-D (1-4), which contain an unusual bicyclo[5.2.1(4,10)] decane motif in the tetranortriterpenoid core, and trisinenmalins A-C and E-I (5-7 and 10-14), together with the known compounds 15-acetyltrichagmalin C (8) and trisinenmalin D (9), were isolated from the roots of Trichilia sinensis. Their structures were determined on the basis of the analysis of MS and NMR spectroscopic data, as well as by comparison with the literature. Compounds 5-7 and 10-14 displayed weak inhibitory activity against selected tumor cell lines. Compounds 2-4, 6-9 and 12-14 exhibited weak acetylcholinesterase-inhibiting activity in vitro.

分类号： O6

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