Complete genome sequence of Streptomyces griseochromogenes ATCC 14511(T), a producer of nucleoside compounds and diverse secondary metabolites

文献类型: 外文期刊

第一作者: Wu Lijuan

作者: Wu Lijuan;Chen, Guoqing;Feng, Guozhong

作者机构:

关键词: Streptomyces;Genome sequence;Nucleoside antibiotic;Gene cluster

期刊名称:JOURNAL OF BIOTECHNOLOGY ( 影响因子:3.307; 五年影响因子:3.778 )

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收录情况: SCI

摘要: ATCC 14511(T) (=DSM 40499, =NBRC 13413) is a type strain of Streptomyces griseochromogenes. It is known as a producer of nucleoside antibiotic, blasticidin S. In this report we present the complete genome sequence of S. griseochromogenes ATCC 14511(T), which consists of 10,764,674 bp with a linear chromosome, 9822 protein-coding genes, 6 rRNA operons, 74 tRNA and 3 sRNA. The genomic analysis revealed that 52 putative gene clusters are involved in the biosynthesis of secondary metabolites, including four gene clusters of nucleoside antibiotics. These gene clusters provide a beneficial source for production of bioactive natural compounds. (C) 2017 Elsevier B.V. All rights reserved.

分类号: Q81

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