First complete genome sequence of parainfluenza virus 5 isolated from lesser panda

文献类型： 外文期刊

第一作者： Zhai, Jun-Qiong

作者： Zhai, Jun-Qiong;Liu, Jian-Kui;Li, Bing;Zhang, He;Zou, Shu-Zhan;Zhou, Xia;Wu, Meng-Fan;Luo, Man-Lin;Zhai, Shao-Lun;Lin, Tao;Wang, He-Xing;Chen, Wu

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期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）

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收录情况： SCI

摘要： Parainfluenza virus 5 (PIV5) is widespread in mammals and humans. Up to now, there is little information about PIV5 infection in lesser pandas. In this study, a PIV5 variant (named ZJQ-221) was isolated from a lesser panda with respiratory disease in Guangzhou zoo in Guangdong province, southern China. The full-length genome of ZJQ-221 was found to be 15,246 nucleotides and consisted of seven non-overlapping genes encoding eight proteins (i.e., NP, V, P, M, F, SH, HN and L). Sequence alignment and genetic analysis revealed that ZJQ-221 shared a close relationship with a PIV5 strain of canine-origin (1168-1) from South Korea. The findings of this study confirm the presence of PIV5 in lesser panda and indicate this mammal as a possible natural reservoir. Furthermore they highlight the urgent need to strengthen viral surveillance and control of PIV5 in zoo animals.

分类号： R37

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