Induction of copper and iron in acute cold-stimulated brown adipose tissues

文献类型： 外文期刊

第一作者： Wang, Chao

作者： Wang, Chao;Liang, Xiaojuan;Tao, Cong;Yao, Xiaolei;Wang, Yajun;Wang, Yanfang;Li, Kui;Yao, Xiaolei

作者机构：

关键词： Adipose tissues;Copper;Iron;Cold-stimulation;Energy metabolism

期刊名称：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS （ 影响因子：3.575； 五年影响因子：3.381 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Copper (Cu) and iron (Fe), the enzymatic cofactors required for various biochemical processes, have been recently linked to lipid metabolism. Adipose tissues play central roles in energy balance and whether copper and iron homeostasis is involved in cold-stimulated energy metabolism remains unknown. In this study, the Cu and Fe contents in interscapular brown adipose tissue (BAT) and subcutaneous white adipose tissue (subWAT) from mice at different developmental stages were measured. Our results revealed the dynamic changes of Cu and Fe levels during development, suggesting their potential roles in energy homeostasis. Furthermore, the significantly increased Cu and Fe contents and the markedly up regulated CTR1 and ATP7A expression in acute cold-stimulated BAT indicates the involvement of both Cu and Fe in the BAT-mediated thermogenesis. Comparably, no change in the Cu and Fe levels in cold stimulated subWAT was observed at the indicated time points, suggesting that both metals are not involved in the cellular process of cold-induced WAT browning. Taken together, these data demonstrate the induction of Cu and Fe in acute cold-stimulated BAT activation, thus providing the direct evidences of the involvement of copper and iron homeostasis in BAT-mediated non-shivering energy metabolism. (C) 2017 Elsevier Inc. All rights reserved.

分类号： Q5

  • 相关文献

[1]The effects of copper, iron and zinc on digestive enzyme activity in the hybrid tilapia Oreochromis niloticus (L.) x Oreochromis aureus (Steindachner). Li, J. -S.,Li, J. -L.,Wu, T. -T.. 2007

[2]Feeding during the resting phase causes profound changes in physiology and desynchronization between liver and muscle rhythms of rats. Opperhuizen, Anne-Loes,Wang, Dawei,Jansen, Remi,de Vries, Janneke,Kalsbeek, Andries,Wang, Dawei,Foppen, Ewout,Boudzovitch-Surovtseva, Olga,Fliers, Eric,Kalsbeek, Andries. 2016

[3]The detrimental effects of CO2-driven chronic acidification on juvenile Pacific abalone (Haliotis discus hannai). Li, Jiaqi,Mao, Yuze,Jiang, Zengjie,Zhang, Jihong,Fang, Jianguang,Li, Jiaqi,Mao, Yuze,Jiang, Zengjie,Zhang, Jihong,Fang, Jianguang,Bian, Dapeng. 2018

[4]Comparative proteomic and bioinformatic analysis of Theileria luwenshuni and Theileria uilenbergi. Zhang, Xiao,Li, Youquan,Chen, Ze,Liu, Zhijie,Ren, Qiaoyun,Yang, Jifei,Zhu, Xinquan,Guan, Guiquan,Liu, Aihong,Luo, Jianxun,Yin, Hong,Zhang, Xiao,Li, Youquan,Chen, Ze,Liu, Zhijie,Ren, Qiaoyun,Yang, Jifei,Zhu, Xinquan,Guan, Guiquan,Liu, Aihong,Luo, Jianxun,Yin, Hong,Zhang, Xiao,Li, Youquan,Chen, Ze,Liu, Zhijie,Ren, Qiaoyun,Yang, Jifei,Zhu, Xinquan,Guan, Guiquan,Liu, Aihong,Luo, Jianxun,Yin, Hong.

[5]Aluminum chloride caused liver dysfunction and mitochondrial energy metabolism disorder in rat. Xu, Feibo,Liu, Yanfen,Yu, Kaiyuan,Song, Miao,Li, Yanfei,Liu, Yanfen,Zhu, Yanzhu,Zhao, Hansong.

[6]Subtraction suppressive hybridisation analysis of differentially expressed genes associated with puberty in the goat hypothalamus. Cao, G. L.,Feng, T.,Chu, M. X.,Di, R.,Huang, D. W.,Liu, Q. Y.,Hu, W. P.,Wang, X. Y.,Cao, G. L.,Zhang, Y. L.,Feng, T.. 2016

[7]Methanol/sorbitol co-feeding induction enhanced porcine interferon-alpha production by P. pastoris associated with energy metabolism shift. Gao, Min-Jie,Wu, Jian-Rong,Zheng, Zhi-Yong,Shi, Zhong-Ping,Zhan, Xiao-Bei,Lin, Chi-Chung,Li, Zhen,Yu, Rui-Song. 2012

[8]Comparison of blood variables, fiber intensity, and muscle metabolites in hot-boned muscles from electrical- and gas-stunned broilers. Xu, L.,Yue, H. Y.,Wu, S. G.,Zhang, H. J.,Ji, F.,Zhang, L.,Qi, G. H..

[9]Estimation of the maintenance energy requirements, methane emissions and nitrogen utilization efficiency of two suckler cow genotypes. Zou, C. X.,Lively, F. O.,Wylie, A. R. G.,Yan, T.,Zou, C. X..

[10]Wnt gene expression in adult porcine longissimus dorsi and its association with muscle fiber type, energy metabolism, and meat quality. Men Xiao-ming,Deng Bo,Tao Xin,Qi Ke-ke,Xu Zi-wei. 2017

[11]Nutritional and physiological responses of finishing pigs exposed to a permanent heat exposure during three weeks. Hao, Yue,Feng, Yuejin,Yang, Peige,Feng, Jinghai,Gu, Xianhong,Lin, Hai.

[12]Muscle-fibre types in porcine longissimus muscle of different genotypes and their association with the status of energy metabolism. Men, Xiao-Ming,Xu, Zi-Wei,Men, Xiao-Ming,Deng, Bo,Xu, Zi-Wei,Tao, Xin. 2012

[13]PDP1 REGULATES ENERGY METABOLISM THROUGH THE IIS-TOR PATHWAY IN THE RED FLOUR BEETLE, Tribolium castaneum. Li, Zhiqian,Jiang, Jianhao,Chen, Yazhou,You, Lang,Huang, Yongping,Tan, Anjiang,Li, Zhiqian,Jiang, Jianhao,Niu, Baolong,Meng, Zhiqi.

[14]Study on energy metabolism of dairy buffalo heifers in Guangxi, China. Zou, C. X.,Liang, X. W.,Yang, B. Z.,Liang, K.,Wei, S. J.,Zou, C. X.,Liu, J. X.,Xia, Z. S.,Zhao, F.. 2007

[15]Evaluation of tributyltin toxicity in Chinese rare minnow larvae by abnormal behavior, energy metabolism and endoplasmic reticulum stress. Li, Zhi-Hua.

[16]Protein differential expression in the latex from Hevea brasiliensis between self-rooting juvenile clones and donor clones. Li, Hui-Liang,Guo, Dong,Lan, Fang-Ying,Peng, Shi-Qing,Tian, Wei-Min.

[17]The effects of nutritional restriction on neutral lipid accumulation in Chlamydomonas and Chlorella. Deng, Xiaodong,Fei, Xiaowen,Li, Yajun,Fei, Xiaowen. 2011

[18]Titanium as a Beneficial Element for Crop Production. Lyu, Shiheng,Wei, Xiangying,Chen, Jianjun,Pan, Dongming,Lyu, Shiheng,Wei, Xiangying,Chen, Jianjun,Wang, Cun,Wang, Cun,Wang, Xiaoming. 2017

[19]Comparison on cellular mechanisms of iron and cadmium accumulation in rice: prospects for cultivating Fe-rich but Cd-free rice. Gao, Lei,Chang, Jiadong,Chen, Ruijie,Li, Hubo,Lu, Hongfei,Xiong, Jie,Gao, Lei,Chang, Jiadong,Chen, Ruijie,Li, Hubo,Lu, Hongfei,Xiong, Jie,Tao, Longxing. 2016

[20]Structure and expression of transferrin gene of channel catfish, Ictalurus punctatus. Liu, Hong,Takano, Tomokazu,Abernathy, Jason,Wang, Shaolin,Sha, Zhenxia,Jiang, Yanliang,Terhune, Jeffery,Kucuktas, Huseyin,Peatman, Eric,Liu, Zhanjiang,Liu, Hong,Takano, Tomokazu,Abernathy, Jason,Wang, Shaolin,Sha, Zhenxia,Jiang, Yanliang,Terhune, Jeffery,Kucuktas, Huseyin,Peatman, Eric,Liu, Zhanjiang,Liu, Hong,Sha, Zhenxia. 2010

作者其他论文 更多>>

微信小程序