Changes of host DNA methylation in domestic chickens infected with Salmonella enterica

文献类型: 外文期刊

第一作者: Wang, Fei

作者: Wang, Fei;Li, Jianchao;Li, Qinghe;Liu, Ranran;Zheng, Maiqing;Wang, Qiao;Wen, Jie;Zhao, Guiping

作者机构:

关键词: Salmonella enterica infection;chicken;DNA methylation

期刊名称:JOURNAL OF GENETICS ( 影响因子:1.166; 五年影响因子:1.212 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: Cytosine methylation is an effective way to modulate gene transcription. However, very little is known about the epigenetic changes in the host that is infected with Salmonella enterica. In this study, we used methylated DNA immunoprecipitation sequencing to analyse the genomewide DNA methylation changes in domestic chickens after infected with Salmonella. The level of DNA methylation was slightly higher in the genomic regions around the transcription start termination sites in a Salmonella-infected group compared to the controls. Overall, 879 peaks were differentially methylated between Salmonella-infected and control groups, among which 135 were located in the gene promoter regions. Genes including MHC class IV antigen, GABARAPL1, MR1 and KDM1B were shown to be methylated more heavily after infected with Salmonella, whereas DYNLRB2, SEC14L3 and ANKIB1 tended to have fewer methylated cytosine residues in the promoter regions. Gene interaction network analysis of differentially methylated genes in the promoter regions revealed extensive connections with immune-related genes, indicating the possible impact of infection with Salmonella on the epigenetic status of the host.

分类号: Q3

  • 相关文献

[1]DNA methylation-mediated transcription factors regulate Piwil1 expression during chicken spermatogenesis. Qiu, Lingling,Xu, Lu,Chang, Guobin,Gu, Qixin,Bi, Yulin,Zhang, Yu,Lu, Wei,Ren, Lichen,Zhu, Pengfei,Mu, Yun,Zhang, Yang,Xu, Qi,Chen, Guohong,Liu, Xiangping,Wang, Hongzhi,Wang, Kehua.

[2]Folate supplementation modifies CCAAT/enhancer-binding protein alpha methylation to mediate differentiation of preadipocytes in chickens. Wen, Jie.

[3]DNA methylation and NF-Y regulate Piwil1 expression during chicken spermatogenesis. Chang, Guobin,Chen, Rong,Xu, Lu,Ma, Teng,Wang, Hongzhi,Chen, Jing,Zhang, Yang,Li, Zhiteng,Wan, Fang,Guo, Xiaomin,Xu, Qi,Zhao, Wenming,Chen, Guohong,Chen, Rong.

[4]Rapid alterations of gene expression and cytosine methylation in newly synthesized Brassica napus allopolyploids. Xu, Yanhao,Zhong, Lan,Wang, Jianbo,Wu, Xiaoming,Fang, Xiaoping.

[5]Widespread and evolutionary analysis of a MITE family Monkey King in Brassicaceae. Dai, Shutao,Hou, Jinna,Long, Yan,Wang, Jing,Li, Cong,Xiao, Qinqin,Jiang, Xiaoxue,Zou, Xiaoxiao,Zou, Jun,Meng, Jinling,Hou, Jinna. 2015

[6]Genome-wide high-resolution mapping of DNA methylation identifies epigenetic variation across embryo and endosperm in Maize (Zea may). Wang, Pengfei,Ma, Chuanxi,Wang, Pengfei,Xia, Han,Zhang, Ye,Zhao, Shuzhen,Zhao, Chuanzhi,Hou, Lei,Li, Changsheng,Li, Aiqin,Wang, Xingjun. 2015

[7]Synonymous Codon Usage Bias in the Plastid Genome is Unrelated to Gene Structure and Shows Evolutionary Heterogeneity. Qi, Yueying,Xu, Wenjing,Xing, Tian,Zhao, Mingming,Yan, Li,Xia, Guangmin,Wang, Mengcheng,Li, Nana. 2015

[8]Alteration of the DNA methylation status of donor cells impairs the developmental competence of porcine cloned embryos. Huan, Yan Jun,Zhu, Jiang,Xie, Bing Teng,Wang, Jian Yu,Li, Jing Yu,Xue, Bing Hua,Kong, Qing Ran,Liu, Zhong Hua,Huan, Yan Jun,Wu, Zhan Feng,Zhang, Ji Guang.

[9]Study on DNA Cytosine Methylation of Cotton (Gossypium hirsutum L.) Genome and Its Implication for Salt Tolerance. ZHAO Yun-lei,YU Shu-xun,YE Wu-wei,WANG Hong-mei,WANG Jun-juan,FANG Bao-xing. 2010

[10]Induced Pib Expression and Resistance to Magnaporthe grisea are Compromised by Cytosine Demethylation at Critical Promoter Regions in Rice. Li, Yuan,Xia, Qiong,Wu, Ying,Xu, Chunming,Liu, Bao,Li, Yuan,Xia, Qiong,Wu, Ying,Xu, Chunming,Liu, Bao,Kou, Hongping,Wang, Dan,Lin, Xiuyun,Xing, Shaochen. 2011

[11]Effect of different light quality on DNA methylation variation for brown cotton (Gossypium hirstum). Li, Tingchun,Fan, Honghong,Li, Zhengpeng,Wei, Jun,Cai, Yongping,Lin, Yi,Li, Tingchun. 2011

[12]Laser Irradiation-Induced DNA Methylation Changes Are Heritable and Accompanied with Transpositional Activation of mPing in Rice. Li, Siyuan,Xia, Qiong,Yu, Xiaoming,Gao, Xiang,Liu, Bao,Li, Siyuan,Wang, Fang,Ma, Jian,Kou, Hongping,Lin, Xiuyun. 2017

[13]Performances of Different Fragment Sizes for Reduced Representation Bisulfite Sequencing in Pigs. Yuan, Xiao-Long,Zhang, Zhe,Pan, Rong-Yang,Gao, Ning,Deng, Xi,Li, Bin,Zhang, Hao,Li, Jia-Qi,Yuan, Xiao-Long,Sangild, Per Torp,Gao, Ning. 2017

[14]Molecular characterizations of DNA methyltransferase 3 and its roles in temperature tolerance in the whitefly, Bemisia tabaci Mediterranean. Hong, X. -Y.,Dai, T. -M,Lu, Z. -C.,Wang, Y. -S.,Liu, W. -X.,Wan, F. -H.,Wan, F. -H.. 2018

[15]Promoter methylation negatively correlated with mRNA expression but not tissue differential expression after heat stress. Gan, J. K.,Zhang, D. X.,Zhang, X. Q.,Chen, Z. Y.,Luo, Q. B.,Gan, J. K.,Zhang, D. X.,He, D. L.,Zhang, X. Q.,Chen, Z. Y.,Luo, Q. B.,He, D. L.. 2013

[16]Mutation of the RDR1 gene caused genome-wide changes in gene expression, regional variation in small RNA clusters and localized alteration in DNA methylation in rice. Wang, Ningning,Zhang, Di,Wang, Zhenhui,Xun, Hongwei,Wang, Hui,Huang, Wei,Liu, Ying,Li, Ning,Ou, Xiufang,Zhang, Chunyu,Liu, Bao,Wang, Ningning,Ma, Jian,Lin, Xiuyun,Zhang, Chunyu,Wang, Ningning,Wang, Ming-Bo. 2014

[17]A Comparative Analysis of DNA Methylation in Diploid and Tetraploid Apple (Malus x domestica Borkh.). He, Ping,Cheng, Lailiang,Li, Huifeng,Wang, Haibo,Li, Linguang. 2017

[18]Comparative analysis of DNA methylation changes in two rice genotypes under salt stress and subsequent recovery. Wang, Wensheng,Huang, Fei,Qin, Qiao,Zhao, Xiuqin,Li, Zhikang,Fu, Binying,Li, Zhikang,Fu, Binying.

[19]Expression and methylation of microsomal triglyceride transfer protein and acetyl-CoA carboxylase are associated with fatty liver syndrome in chicken. Liu, Zhen,Li, Qinghe,Liu, Ranran,Zhao, Guiping,Zhang, Yonghong,Zheng, Maiqing,Cui, Huanxian,Li, Peng,Cui, Xiaoyan,Liu, Jie,Wen, Jie,Liu, Zhen,Li, Qinghe,Liu, Ranran,Zhao, Guiping,Zheng, Maiqing,Cui, Huanxian,Li, Peng,Cui, Xiaoyan,Liu, Jie,Wen, Jie,Zhang, Yonghong.

[20]Polymorphisms and DNA methylation level in the CpG site of the GHR1 gene associated with mRNA expression, growth traits and hormone level of half-smooth tongue sole (Cynoglossus semilaevis). Zhao, J. L.,Si, Y. F.,He, F.,Wen, H. S.,Li, J. F.,Ren, Y. Y.,Zhao, M. L.,Huang, Z. J.,Zhao, J. L.,Si, Y. F.,He, F.,Wen, H. S.,Li, J. F.,Ren, Y. Y.,Zhao, M. L.,Huang, Z. J.,Chen, S. L..

作者其他论文 更多>>