Influence of phytochemicals on the biocompatibility of inorganic nanoparticles: a state-of-the-art review

文献类型： 外文期刊

第一作者： Cao, Yi

作者： Cao, Yi;Xie, Yixi;Li, Yining;Zhang, Cao;Fang, Xin;Zhou, Yiwei;Cao, Yi;Xie, Yixi;Liu, Liangliang;Xiao, Aiping;Fang, Xin;Zhou, Yiwei

作者机构：

关键词： Nanoparticles (NPs);Phytochemicals;Surface coating;Biocompatibility;Oxidative stress

期刊名称：PHYTOCHEMISTRY REVIEWS （ 影响因子：5.374； 五年影响因子：6.048 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Abstract Inorganic nanoparticles (NPs) are among the most produced NPs that could be used in consumer products and as healthcare materials, however, the intrinsic toxicity particularly through the mechanism associated oxidative stress raises the health concern about inorganic NP exposure. Phytochemicals are bioactive metabolites derived from plants as well as non-pathogenic microorganisms living within plants and have been shown to be beneficial to human health with their anti-aging, anti-cancer, anti-inflammation and anti-oxidant properties. In the present review, the influence of on the biocompatibility of inorganic NPs was discussed. It has been shown that phytochemicals could be used as bio-friendly capping agents for green synthesis of inorganic NPs, and phytochemical coated inorganic NPs were remarkable stable and biocompatible with high therapeutic efficiency. Meanwhile, the presence of phytochemicals was also able to reduce the side effects and enhance the therapeutic abilities of inorganic NPs, which is likely attributed to the anti-oxidative properties of phytochemicals. Thus, using phytochemicals could be a promising and plausible way to reduce side effects and increase the biocompatibility of inorganic NPs for biomedical applications.

分类号： Q94

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