New antibacterial depsidones from an ant-derived fungus Spiromastix sp. MY-1

文献类型: 外文期刊

第一作者: Guo, Zhi-Kai

作者: Guo, Zhi-Kai;Zhu, Wen-Yong;Zhao, Li-Xing;Chen, Yan-Chi;Li, Sui-Jun;Cheng, Ping;Ge, Hui-Ming;Tan, Ren-Xiang;Jiao, Rui-Hua;Guo, Zhi-Kai;Zhu, Wen-Yong;Zhao, Li-Xing

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关键词: Fungus; Spiromastix sp.; Depsidones; Phytopathogenic bacteria; Antibacterial

期刊名称:CHINESE JOURNAL OF NATURAL MEDICINES ( 影响因子:3.887; 五年影响因子:3.273 )

ISSN: 2095-6975

年卷期: 2022 年 20 卷 8 期

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收录情况: SCI

摘要: Six new (1-6) and seven known depsidones (7-13) were isolated from the culture of an ant (Monomorium chinensis)-derived fungus Spiromastix sp. MY-1. Their structures were elucidated by extensive spectroscopic analysis including high resolution MS, 1D and 2D NMR data. The new bromide depsidones were obtained through supplementing potassium bromide in the fermentation medium of Spiromastix sp. MY-1. All isolated compounds showed various bioactivities against the tested phytopathogenic bacteria. Particularly, new bromide compound 4, named spiromastixone S, exhibited the strongest activity against Xanthomonas oryzae pv. oryzae with a MIC value of 5.2 mu mol.L-1.

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