Purification, NMR Study and Immunostimulating Property of a Fucogalactan from the Fruiting Bodies of Ganoderma lucidum

文献类型： 外文期刊

第一作者： Ye, Libin

作者： Ye, Libin;Zhang, JingSong;Yang, Yan;Zhou, Shuai;Jia, Wei;Hao, RuiXia;Ye, Libin;Zhou, Kan;Pan, Yinglie

作者机构：

关键词： Ganoderma lucidum;Ganodermataceae;polysaccharide;fucogalactan;NMR;immunostimulating property

期刊名称：PLANTA MEDICA （ 影响因子：3.352； 五年影响因子：3.4 ）

ISSN： 0032-0943

年卷期： 2008 年 74 卷 14 期

页码：

收录情况： SCI

摘要： A water-soluble polysaccharide (LZ-D-1) was isolated from Ganoderma lucidum fruiting bodies by DEAE-Sepharose Fast Flow and Sephacryl S-300 high-resolution chromatography. The polysaccharide had a molecular weight of 2.8 x 10(4) Da and was mainly composed Of (L)-Fuc, (D)-Glc and (D)-Gal in a molar ratio of ca.1 : 1 : 5. LZ-D-1 had a sugar content of 98.7% as measured using the phenol-sulfuric acid method. On the basis of methylation analysis, FT-IR spectrum and NMR experiments, the Structure of the repeating unit of the polysaccharide was established. LZ-D-1 had a backbone composed of 1,6-disubstituted alpha-D-galactopyranosyl, 1,2,6-trisubstituted alpha-D-galactopyranosyl and had a branch composed of fucose attached to 0-2 of a 1,2,6-trisubstituted (x-L)-galactopyranosyl residue. At the same time, the polysaccharide contained some 1,6-disubstituted glucopyranosyl residues and 1,3-disubstituted glucopyranosyl residues. An immunostimulating experiment in vitro indicated that D-1 stimulated proliferation of mouse spleen lymphocytes.

分类号：

  • 相关文献

[1]NMR characterization for polysaccharide moiety of a glycopeptide. Zhang, Jingsong,Ye, Libin,Li, Jianrong,Pan, Yingjie. 2010

[2]Structural Characterisation Of A Heteropolysaccharide By Nmr Spectra. Ye, LiBin,Zhang, JingSong,Yang, Yan,Zhou, Shuai,Liu, YanFang,Tang, Qinglui,Du, Xiuju,Chen, Hui,Ye, LiBin,Du, Xiuju,Pan, YingJie.

[3]Structural elucidation of a novel fucogalactan that contains 3-O-methyl rhamnose isolated from the fruiting bodies of the fungus, Hericium erinaceus. Zhang, AQ,Zhang, JS,Tang, QU,Jia, W,Yang, Y,Liu, YF,Fan, JM,Pan, YJ. 2006

[4]Structural elucidation of a neutral fucogalactan from the mycelium of Coprinus comatus. Fan, JM,Zhang, JS,Tang, QJ,Liu, YF,Zhang, AQ,Pan, YJ.

[5]Isolation, Purification, and Immunological Activities of a Low-Molecular-Weight Polysaccharide from the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Higher Basidiomycetes). Zhu, Lina,Luo, Xi,Tang, Qingjiu,Liu, Yanfang,Zhou, Shuai,Yang, Yan,Zhang, Jingsong,Zhu, Lina,Luo, Xi,Tang, Qingjiu,Liu, Yanfang,Zhou, Shuai,Yang, Yan,Zhang, Jingsong,Zhu, Lina,Luo, Xi. 2013

[6]Antioxidant activity of polysaccharide extracted from Ganoderma lucidum using response surface methodology. Kan, Yongjun,Wu, Jinzhong,Wu, Yanbin,Wu, Jianguo,Wu, Jinzhong,Chen, Tiqiang.

[7]Breeding of new Ganodernia lucidum strains simultaneously rich in polysaccharides and triterpenes by mating basidiospore-derived monokaryons of two commercial cultivars. Ke, Bin-Rong,Liu, Xin-Rui,Wu, Xiao-Ping,Liu, Sheng-Rong,Zhang, Wei-Rui,Ke, Bin-Rong.

[8]Molecular phylogeny and morphology reveal a new species of Amauroderma (Basidiomycota) from China. Xing, Jia-Hui,Cui, Bao-Kai,He, Xiao-Lan,Decock, Cony.

[9]Lanostane-type triterpenoids from the fruiting body of Ganoderma calidophilum. Huang, Sheng-Zhuo,Ma, Qing-Yun,Kong, Fan-Dong,Guo, Zhi-Kai,Cai, Cai-Hong,Hu, Li-Li,Zhou, Li-Man,Wang, Qi,Dai, Hao-Fu,Mei, Wen-Li,Zhao, You-Xing. 2017

[10]Chemical constituents from the fruiting bodies of Amauroderma subresinosum. Wang, Qiao,Wang, Yu-Guang,Ma, Qing-Yun,Huang, Sheng-Zhuo,Kong, Fan-Dong,Zhou, Li-Man,Dai, Hao-Fu,Zhao, You-Xing,Wang, Qiao.

[11]Chemical constituents from the fungus Amauroderma amoiensis and their in vitro acetylcholinesterase inhibitory activities. Zhang, Shuang Shuang,Ma, Qing Yun,Dai, Hao Fu,Huang, Sheng Zhuo,Luo, Ying,Zhao, You Xing,Zhang, Shuang Shuang,Yu, Zhi Fang,Zou, Xi Sheng,Luo, Huai Rong.

[12]Two New Tirucallane Triterpenoids from the Fruiting Bodies of Ganoderma tropicum. Ma, Qing-Yun,Huang, Sheng-Zhuo,Hu, Li-Li,Guo, Zhi-Kai,Dai, Hao-Fu,Zhao, You Xing.

[13]A new nortriterpenoid from the fruiting bodies of Ganoderma tropicum. Hu, Li-li,Ma, Qing-yun,Huang, Sheng-zhuo,Guo, Zhi-kai,Ma, Hai-xia,Guo, Jian-chun,Dai, Hao-fu,Zhao, You-xing,Hu, Li-li.

[14]Three new lanostanoid triterpenes from the fruiting bodies of Ganoderma tropicum. Hu, Li-Li,Ma, Qing-Yun,Huang, Sheng-Zhuo,Guo, Zhi-Kai,Ma, Hai-Xia,Guo, Jian-Chun,Dai, Hao-Fu,Zhao, You-Xing,Hu, Li-Li.

[15]Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3. Ji, Zhe,Tang, Qingju,Hao, Ruixa,Zhang, Jinsong,Ji, Zhe,Pan, Yingje. 2011

[16]Development of a stable SCAR marker for rapid identification of Ganoderma lucidum Hunong 5 cultivar using DNA pooling method and inter-simple sequence repeat markers. Chao Wen-zheng,Yu Ling,Tang Chuan-hong,Zhang Jing-song,Tang Chuan-hong,Honda, Yoichi. 2018

[17]Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum. Dai, Jian,Miller, Matthew A.,Everetts, Nicholas J.,Wang, Xia,Yao, Guang,Li, Peng,Xu, Jian-Hua,Li, Peng,Xu, Jian-Hua,Li, Ye,Dai, Jian,Yao, Guang. 2017

[18]A novel Ganoderma lucidum G0119 fermentation strategy for enhanced triterpenes production by statistical process optimization and addition of oleic acid. Feng, Jie,Zhang, Jing-Song,Feng, Na,Yan, Meng-Qiu,Yang, Yan,Jia, Wei,Lin, Chi-Chung,Feng, Jie,Zhang, Jing-Song,Feng, Na,Yan, Meng-Qiu,Yang, Yan,Jia, Wei,Lin, Chi-Chung,Feng, Jie,Zhang, Jing-Song,Feng, Na,Yan, Meng-Qiu,Yang, Yan,Jia, Wei,Lin, Chi-Chung.

[19]Molecular cloning, characterization, and function analysis of a mevalonate pyrophosphate decarboxylase gene from Ganoderma lucidum. Shi, Liang,Qin, Lei,Ren, Ang,Fang, Xing,Mu, Dashuai,Zhao, Mingwen,Xu, Yingjie,Tan, Qi.

[20]Structural elucidation of the polysaccharide moiety of a glycopeptide (GLPCW-II) from Ganoderma lucidum fruiting bodies. Ye, LiBin,Zhang, JingSong,Tang, QingJiu,Liu, YanFang,Ye, LiBin,Du, XiuJui,Ye, XiJun,Gong, ChunYu,Pan, YingJie.

作者其他论文 更多>>

微信小程序