Ginseng soluble dietary fiber can regulate the intestinal flora structure, promote colon health, affect appetite and glucolipid metabolism in rats

文献类型: 外文期刊

第一作者: Hua, Mei

作者: Hua, Mei;Li, Zhiman;Sha, Jiyue;Li, Shanshan;Sun, Yinshi;Fan, Meiling;Fan, Meiling

作者机构:

关键词: Ginseng-SDF; Colon health; Prebiotics; SCFAs; Ghrelin; Glucolipid metabolism

期刊名称:JOURNAL OF FUNCTIONAL FOODS ( 影响因子:4.451; 五年影响因子:4.908 )

ISSN: 1756-4646

年卷期: 2021 年 83 卷

页码:

收录情况: SCI

摘要: In this study, the effects of ginseng water-soluble dietary fiber (ginseng-SDF) on metabolism, appetite and colon health in rats were investigated. The results showed that ginseng-SDF could improve the glucolipid metabolism, especially in the triglyceride levels. Ginseng-SDF also increased satiety and delayed gastric emptying by regulating the appetite hormone levels as ghrelin, glucagon-like peptide-1, peptide YY, and cholecystokinin. In addition, ginseng-SDF improved intestinal structures and enhanced fecal short-chain fatty acids concentrations (especially acetic acid and butyric acid). More importantly, ginseng-SDF affected the abundance of Firmicutes and Bacteroides, and significantly promoted the proliferation of probiotics and cellulolytic bacteria such as Lactobacillus, Bifidobacterium and Ruminococcus_bromii. Among them, Bifidobacterium pseudolongum, Lactobacillus helveticus and R. bromii were correlated with blood glucose and blood lipid levels. These results suggested that ginseng-SDF could alter the intestinal flora structure, promote colon health, and ultimately have a positive impact on glucolipid metabolism and energy homeostasis.

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