Detection of candidate genes for growth and carcass traits using genome-wide association strategy in Chinese Simmental beef cattle
文献类型: 外文期刊
第一作者: Zhang, Wengang
作者: Zhang, Wengang;Xu, Lingyang;Gao, Huijiang;Wu, Yang;Gao, Xue;Zhang, Lupei;Zhu, Bo;Song, Yuxin;Li, Junya;Chen, Yan;Wu, Yang;Bao, Jinshan
作者机构:
关键词: Average Daily Gain;Dressing Percentage;Genome-wide Association Study;Quantitative Trait Loci
期刊名称:ANIMAL PRODUCTION SCIENCE ( 影响因子:1.533; 五年影响因子:1.779 )
ISSN: 1836-0939
年卷期: 2018 年 58 卷 2 期
页码:
收录情况: SCI
摘要: In Chinese beef cattle industry, there are more than 60 million livestock, nearly half of which are Chinese Simmental beef cattle or Simmental crossbreds. Over the past decades, numerous quantitative trait loci for economic traits in cattle have been identified, while few studies for growth and carcass traits have been reported in Simmental beef cattle. In the present study, we conducted genome-wide association study based on BovineHD BeadChip and identified 41, 15, 3, 22 and 16 single-nucleotide polymorphisms significantly associated with average daily gain, liveweight before slaughter, carcass weight, dressing percentage and pure meat percentage respectively. In total, 18 candidate genes were found for growth and carcass traits, and four haplotype blocks for growth and carcass traits were discovered. These findings will facilitate detection of major genes and genetic variants involved in growth and carcass traits of beef cattle in further studies.
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