Non-structural protein 2 of the porcine reproductive and respiratory syndrome (PRRS) virus: A crucial protein in viral pathogenesis, immunity and diagnosis

文献类型： 外文期刊

第一作者： Wang, Feng-Xue

作者： Wang, Feng-Xue;Song, Ni;Chen, Li-Zhi;Cheng, Shi-Peng;Wen, Yong-Jun;Wu, Hua

作者机构：

关键词： Porcine reproductive and respiratory syndrome virus;Non-structural protein 2;Pathogenesis;Immunity;Diagnosis

期刊名称：RESEARCH IN VETERINARY SCIENCE （ 影响因子：2.534； 五年影响因子：2.382 ）

ISSN： 0034-5288

年卷期： 2013 年 95 卷 1 期

页码：

收录情况： SCI

摘要： Porcine reproductive and respiratory syndrome (PRRS) is a swine disease of significant economic importance that causes reproductive and respiratory problems in pigs. The replicase non-structural protein 2 (Nsp2) of the porcine reproductive and respiratory syndrome virus (PRRSV) is recognized as the most variable region within the PRRSV genome. This review discusses the molecular characteristics and biological and immunological functions of the PRRSV Nsp2 and its involvement in the virus's pathogenesis. The role of Nsp2 in cell and tissue tropism, replication and growth, and variation and pathogenicity of PRRSV and the differences in virulence among different strains are described in the present review. Nsp2 is an ideal marker for monitoring genetic variation and for developing differential diagnostic tests. (c) 2013 Elsevier Ltd. All rights reserved.

分类号：

  • 相关文献

[1]Clostridium infection (Jisizheng) in yaks in Qinghai, China. Qiu, CQ,Yang, XL.

[2]Fowl adenovirus serotype 4: Epidemiology, pathogenesis, diagnostic detection, and vaccine strategies. Li, P. H.,Zheng, P. P.,Zhang, T. F.,Wen, G. Y.,Shao, H. B.,Luo, Q. P.,Li, P. H.,Zheng, P. P.,Zhang, T. F.,Wen, G. Y.,Shao, H. B.,Luo, Q. P..

[3]Biotechnological advances in the diagnosis, species differentiation and phylogenetic analysis of Schistosoma spp.. Zhao, Guang-Hui,Li, Juan,Li, Xiao-Yan,Zhu, Xing-Quan,Zhao, Guang-Hui,Li, Juan,Lin, Rui-Qing,Blair, David,Li, Xiao-Yan,Elsheikha, Hany M.,Zou, Feng-Cai,Zhu, Xing-Quan. 2012

[4]Monoclonal antibodies for differentiating infections of three serological-related tospoviruses prevalent in Southwestern China. Chen, Yu-Han,Chien, Wan-Chu,Sun, Jing-Hua,Wang, Yun-Chi,Chen, Tsung-Chi,Dong, Jiahong,Zheng, Kuanyu,Wu, Kuo,Yeh, Shyi-Dong,Yeh, Shyi-Dong,Chen, Tsung-Chi. 2016

[5]Nested-PCR assay for detection of Schistosoma japonicum infection in domestic animals. Zhang, Xin,He, Chuan-Chuan,Liu, Jin-Ming,Li, Hao,Lu, Ke,Fu, Zhi-Qiang,Zhu, Chuan-Gang,Hong, Yang,Jin, Ya-Mei,Lin, Jiao-Jiao,Liu, Yi-Ping,Tong, Lai-Bao,Zhou, De-bao,Zha, Li,Lin, Jiao-Jiao. 2017

[6]Detection of anti-Trichinella antibodies in serum of experimentally-infected swine by immunochromatographic strip. Fu, B. Q.,Li, W. H.,Gai, W. Y.,Yao, J. X.,Qu, Z. G.,Xie, Z. Z.,Wang, Y. H.,Zhang, D. L.,Blaga, R.. 2013

[7]Classical swine fever in China: A minireview. Luo, Yuzi,Li, Su,Sun, Yuan,Qiu, Hua-Ji.

[8]A candidate recombinant antigen for diagnosis of schistosomiasis japonica in domestic animals. Feng, Jintao,Xu, Rui,Zhang, Xin,Han, Yu,He, Chuanchuan,Lu, Chao,Hong, Yang,Lu, Ke,Li, Hao,Jin, Yamei,Lin, Jiaojiao,Liu, Jinming,Lin, Jiaojiao.

[9]Rapid diagnosis of Theileria annulata by recombinase polymerase amplification combined with a lateral flow strip (LF-RPA) in epidemic regions. Yin, Fangyuan,Liu, Junlong,Liu, Aihong,Li, Youquan,Luo, Jianxun,Guan, Guiquan,Yin, Hong,Yin, Hong.

[10]Loop-mediated isothermal amplification for rapid and convenient detection of Mycoplasma hyopneumoniae. Li, Jiahe,Jiang, Fei,Yang, Sheng,Guo, Panpan,Wu, Wenxue,Minion, F. Chris,Petersen, Andrew C.,Li, Jinxiang.

[11]Chemiluminescence Immunoassay for the Detection of Antibodies against the 2C and 3ABC Nonstructural Proteins Induced by Infecting Pigs with Foot-and-Mouth Disease Virus. Liu, Zezhong,Shao, Junjun,Zhao, Furong,Zhou, Guangqing,Gao, Shandian,Liu, Wei,Lv, Jianliang,Li, Yangfan,Chang, Huiyun,Zhang, Yongguang,Zhang, Yongguang,Li, Xiumei.

[12]Diagnosis of toxoplasmosis and typing of Toxoplasma gondii. Liu, Quan,Zhu, Xing-Quan,Liu, Quan,Wang, Ze-Dong,Huang, Si-Yang,Zhu, Xing-Quan. 2015

[13]Evaluation of different nested PCRs for detection of Anaplasma phagocytophilum in ruminants and ticks. Yang, Jifei,Liu, Zhijie,Niu, Qingli,Liu, Junlong,Xie, Jingying,Chen, Qiuyu,Chen, Ze,Guan, Guiquan,Liu, Guangyuan,Luo, Jianxun,Yin, Hong,Yin, Hong. 2016

[14]Evaluation of recombinant multi-epitope proteins for diagnosis of goat schistosomiasis by enzyme-linked immunosorbent assay. Lv, Chao,Hong, Yang,Fu, Zhiqiang,Lu, Ke,Cao, Xiaodan,Wang, Tao,Zhu, Chuangang,Li, Hao,Xu, Rui,Jia, Bingguang,Han, Qian,Dou, Xuefeng,Shen, Yuanxi,Zhang, Zuhang,Zai, Jinli,Feng, Jintao,Lin, Jiaojiao,Lin, Jiaojiao,Lv, Chao,Dou, Xuefeng,Shen, Yuanxi. 2016

[15]Expression analysis and biological characterization of Babesia sp BQ1 (Lintan) (Babesia motasi-like) rhoptry-associated protein 1 and its potential use in serodiagnosis via ELISA. Niu, Qingli,Liu, Zhijie,Yang, Jifei,Yu, Peifa,Pan, Yuping,Zhai, Bintao,Luo, Jianxun,Guan, Guiquan,Yin, Hong,Yin, Hong,Moreau, Emmanuelle. 2016

[16]Deep sequencing-based identification of pathogen-specific microRNAs in the plasma of rabbits infected with Schistosoma japonicum. Cheng, Guofeng,Luo, Rong,Hu, Chao,Cao, Jie,Jin, Youxin. 2013

[17]Research progress on surface antigen 1 (SAG1) of Toxoplasma gondii. Wang, Yanhua,Yin, Hong. 2014

[18]Control of swine pseudorabies in China: Opportunities and limitations. Sun, Yuan,Luo, Yuzi,Wang, Chun-Hua,Yuan, Jin,Li, Na,Song, Kun,Qiu, Hua-Ji.

[19]Confirmation and Sequence analysis of N gene of PPRV in South Xinjiang, China. Liu, YongHong,Li, XianQiang,Zhang, Luyao,Li, Fei,Zhao, Li,Yang, Bo,Wang, XueFeng. 2017

[20]Infection of wampee and lemon by the Citrus Huanglongbing pathogen (Candidatus Liberibacter asiaticus) in China. Ding, F,Wang, G,Yi, G,Zhong, Y,Zeng, J,Zhou, B. 2005

作者其他论文 更多>>

微信小程序