EVALUATION OF CYTOTOXICITY OF NATURAL NANO-ATTAPULGITE AND ITS ENHANCEMENT OF VERO CELL PRODUCTIVITY

文献类型: 外文期刊

第一作者: He, Li

作者: He, Li;Ding, Kejian;Wu, Hao;Wang, Nan;Williams, Corey;Yan, Qiong;Li, Xiangchen;Guan, Weijun;Wu, Guosong;Chu, Paul K.

作者机构:

关键词: Attapulgite;Cytotoxicity;Cell Cultivation;Cell viability

期刊名称:DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES ( 影响因子:0.963; 五年影响因子:1.047 )

ISSN: 1842-3582

年卷期: 2013 年 8 卷 2 期

页码:

收录情况: SCI

摘要: Natural Nano-attapulgite (NATP) is widely used industrially due to its high specific surface area. To determine its potential in the large-scale mammalian cell culture and tissue engineering, the cytotoxicity of NATP is evaluated using African green monkey kidney (VERO) cells on both the cellular and molecular levels. Our researches show that NATP not only does not exhibit any cytotoxicity, but also substantially enhances proliferation of VERO cells which is useful to pare the production cost of biomedical products. These results suggest that nano-attapulgite can serve as potential in large-scale mammalian cell cultures and tissue engineering, respectively.

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