Optimization of nobiletin extraction assisted by microwave from orange byproduct using response surface methodology

文献类型： 外文期刊

第一作者： Zhang, Yu

作者： Zhang, Yu;Li, Hongjun;He, Zhifei;Zhang, Yu;Dou, Huating;Wu, Houjiu;Sun, Zhigao;Wang, Hua;Huang, Xuegen;Ma, Yaqin

作者机构：

关键词： microwave-assisted extraction;peel of sweet orange;nobiletin extraction;response surface methodology

期刊名称：FOOD SCIENCE AND BIOTECHNOLOGY （ 影响因子：2.391； 五年影响因子：2.108 ）

ISSN： 1226-7708

年卷期： 2013 年 22 卷 1 期

页码：

收录情况： SCI

摘要： Nobiletin (NOB) is a well-known polymethoxylated flavone that has only been found in citrus. The objective of this study is to obtain the optimal conditions for extracting nobiletin from sweet orange residues by microwave-assisted extraction (MAE) using response surface method. By using the Box-Behnken experimental design and SAS software 3 independent variables including solid/solvent ratio, microwave power, and treatment time were examined for the response variable nobiletin extraction yield. The regression Eq. 7 statistically significant (p < 0.001) and R-2 was 0.9189. Based on our regression result and considering the feasibility of experiment conduction, we chose the following independent variable values as the optimized conditions for the extraction of NOB: 1:21.91 (g/mL) for the solid/solvent ratio, 14.16 min for the treatment time, and 693.72 W for the microwave power. Under these conditions, the nobiletin yield of 267.8 mu g/g of byproduct was achieved.

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