Genetic Polymorphisms of Mc4R and IGF2 Gene Association with Feed Conversion Efficiency Traits in Beef Cattle
文献类型: 外文期刊
第一作者: Du, Xin-hua
作者: Du, Xin-hua;Chen, Cui;Yuan, Zheng-rong;Zhang, Li-min;Chen, Xiao-jie;Wang, Yan-hui;Gao, Xue;Zhang, Lu-pei;Gao, Hui-jiang;Li, Jun-ya;Xu, Shang-zhong
作者机构:
关键词: Beef cattle;Feed conversion efficiency;IGF2;MALDI-TOF-MS;MC4R
期刊名称:PAKISTAN VETERINARY JOURNAL ( 影响因子:1.318; 五年影响因子:0.954 )
ISSN: 0253-8318
年卷期: 2013 年 33 卷 4 期
页码:
收录情况: SCI
摘要: Melanocortin-4 receptor (MC4R) gene is part of the central melanocortin pathway located in the hypothalamus, an area of the brain in which appetite is regulated. Insulin-like growth factor 2 (IGF2) gene plays a role in muscle growth, myoblast proliferation and differentiation. Thus, they are candidate genes for feed conversion efficiency (FCE). The study was to investigate the effects of variants in cattle MC4R and IGF2 gene on FCE traits including residual feed intake (RFI), feed conversion ratio (FCR) and average daily gain (ADG). We screened single nucleotide polymorphisms (SNPs) of the two genes in 118 Simmental bulls by DNA-pool sequencing and genotyped by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis. C1069G locus of MC4R and four SNPs (C2209T, G18587C, A22950T and G26920T) of IGF2 were identified in the population. The chi 2 test showed that only MC4R-C1069G, IGF2-C2209T and IGF2-G18587C loci fitted with Hardy-Weinberg equilibrium (P>0.05). General linear model (GLM) was used to analyze differences between genotypes. The results showed that only IGF2-G18587C locus has a significant effect on ADG (P<0.05), but has no significant effect on RFI or FCR (P>0.05). CC and GG genotypes were the dominant genotypes; individual with CC or GG genotype had a larger ADG than GC (P<0.05). (C) 2013 PVJ. All rights reserved
分类号:
- 相关文献
作者其他论文 更多>>
-
3D hot spot construction on the hydrophobic interface with SERS tags for quantitative detection of pesticide residues on food surface
作者:Wang, Yan-Hui;Huang, Chen;Wu, Xiao;Liu, Xiao-Feng;Wang, An;Jin, Shangzhong;Zhang, Fan-Li;You, En-Ming;Liu, Sheng-Hong
关键词:Surface-enhanced Raman scattering; 3D hot spots; Hydrophobic interface; Pesticide residues; Quantitative analysis
-
Transcriptomic and metabolomic analysis of recalcitrant phosphorus solubilization mechanisms in Trametes gibbosa
作者:Chen, Yulan;Farooq, Akasha;Wei, Xieluyao;Qin, Leitao;Wang, Yong;Zhang, Lingzi;Xiang, Quanju;Zhao, Ke;Yu, Xiumei;Chen, Qiang;Penttinen, Petri;Gu, Yunfu;Gao, Xue;Nyima, Tashi
关键词:phosphate solubilizing fungi; transcriptomic analysis; metabolomic analaysis; phosphorus solubilization mechanism; bio-phosphate fertilizer
-
Removal of antibiotic resistance from wastewater in aquatic ecosystems dominated by submerged macrophytes
作者:Zhang, Rong-min;Tan, Hui-zhen;Huang, Wen-qing;Li, Ling-lin;Li, Xin-ting;Xie, Jie;Lian, Xin-lei;Huang, Xian-hui;Zhang, Rong-min;Tan, Hui-zhen;Huang, Wen-qing;Li, Ling-lin;Li, Xin-ting;Xie, Jie;Lian, Xin-lei;Huang, Xian-hui;Chen, Xiao-jie;Li, Ya-fei;Chong, Yun-xiao
关键词:Submerged macrophytes; Antibiotic resistance; Constructed wetland
-
Genome-Wide Scans for Selection Signatures in Ningxia Angus Cattle Reveal Genetic Variants Associated with Economic and Adaptive Traits
作者:Yin, Haiqi;Wang, Yaxuan;Peng, Ruiqi;Wang, Yahui;Zhao, Tong;Zheng, Caihong;Xu, Lingyang;Gao, Xue;Gao, Huijiang;Li, Junya;Wang, Zezhao;Zhang, Lupei;Feng, Yuan;Wang, Yu;Jiang, Qiufei;Zhao, Jie;Zhang, Juan;Chen, Yafei
关键词:Angus cattle; whole-genome resequencing; selection signatures; iHS; immune-related gene; economic trait
-
Multiple strategies association revealed functional candidate FASN gene for fatty acid composition in cattle
作者:Zhu, Bo;Wang, Tianzhen;Niu, Qunhao;Wang, Zezhao;Xu, Lei;Chen, Yan;Zhang, Lupei;Gao, Xue;Gao, Huijiang;Xu, Lingyang;Li, Junya;Zhu, Bo;Hay, El Hamidi;Xu, Lei;Cao, Yang;Zhao, Yumin;Cao, Yang;Zhao, Yumin
关键词:
-
Engineered Plasmonic multi-hot spots on magnetic Nanospheres for quantitative detection of pesticide residues on food surfaces via SERS tagging analysis
作者:Wan, Ming-Jie;Wu, Yu-Ting;Wang, Yan-Hui;Wang, An;Jin, Shangzhong;Zhang, Fan-Li;Wu, Xiao-Hang;Zhang, Yue-Jiao;You, En-Ming;Liu, Sheng-Hong;Chen, Jin-Chao
关键词:Surface-enhanced Raman scattering; Magnetical plasmonic nanostructure; Pesticide residues detection; Raman internal standard; Quantitative analysis
-
Genome-Wide Association Integrating a Transcriptomic Meta-Analysis Suggests That Genes Related to Fat Deposition and Muscle Development Are Closely Associated with Growth in Huaxi Cattle
作者:Liu, Cheng-Li;Ren, Tao;Ruan, Peng-Cheng;Huang, Yong-Fu;Guang-Xin, E.;Liu, Cheng-Li;Zhang, Lu-Pei;Guang-Xin, E.;Ceccobelli, Simone;Huang, De-Jun;Zhang, Lu-Pei
关键词:GWAS; RNA-seq; muscle development; fat deposition; Huaxi cattle