The RNA profile of porcine parvovirus 4, a boca-like virus, is unique among the parvoviruses

文献类型: 外文期刊

第一作者: Cheung, Andrew K.

作者: Cheung, Andrew K.;Long, Jin-Xue;Huang, Lv;Yuan, Shi-Shan

作者机构:

期刊名称:ARCHIVES OF VIROLOGY ( 影响因子:2.574; 五年影响因子:2.466 )

ISSN: 0304-8608

年卷期: 2011 年 156 卷 11 期

页码:

收录情况: SCI

摘要: PPV4 transcribes its genome from a single promoter, and the RNAs are generated via alternate splicing coupled with alternate polyadenylation, a strategy similar to that of the bocaviruses; however, several differences were detected. The PPV4 ORF1 codes for four NS proteins, while the bocavirus ORF1 codes for 1-3 NS proteins. Whereas the VP1/VP2 capsid proteins of bocavirus are encoded by a single RNA, VP1 and VP2 of PPV4 are encoded by two separate RNAs. While ORF3 of PPV4 encodes two NP proteins, ORF3 of bocavirus codes for only one NP polypeptide. Taken together, PPV4 is unique among the parvoviruses.

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