Antioxidant Effects of Oats Avenanthramides on Human Serum

文献类型： 外文期刊

第一作者： Yang Nan

作者： Yang Nan;Hou Zhao-hua;Yao Yang;Zhou Xian-rong;Ren Gui-xing;Liu Sen;Lue Li

作者机构：

关键词： oats avenanthramides;human serum;antioxidation;SOD;MDA;LDL-C;HDL-C

期刊名称：AGRICULTURAL SCIENCES IN CHINA （ 影响因子：0.82； 五年影响因子：0.997 ）

ISSN： 1671-2927

年卷期： 2011 年 10 卷 8 期

页码：

收录情况： SCI

摘要： The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study. Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon. Plasma lipid peroxides and antioxidant status were measured. For 8 capsules (containing 3.12 mg avenanthramides) groups, the levels of serum superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantly increased by 8.4 and 17.9%, respectively (P<0.05), and malondialdehyde (MDA) level significantly decreased by 28.1%. The total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1, 28.1, and 15.1%, respectively (P<0.05). The high density blood lipoprotein cholesterol (HDL-C) levels in the same treat was increased by 13.2%. Based on our research, it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans. It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy.

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