Rapeseed oil fortified with micronutrients reduces atherosclerosis risk factors in rats fed a high-fat diet

文献类型： 外文期刊

第一作者： Xu, Jiqu

作者： Xu, Jiqu;Deng, Qianchun;Huang, Qingde;Yang, Jin'e;Huang, Fenghong;Zhou, Xiaoqi

作者机构：

关键词： Rapeseed oil;Polyphenols;Tocopherols;Phytosterols;Atherosclerosis;Oxidant stress;Plasma lipids;Inflammation

期刊名称：LIPIDS IN HEALTH AND DISEASE （ 影响因子：3.876； 五年影响因子：4.047 ）

ISSN： 1476-511X

年卷期： 2011 年 10 卷

页码：

收录情况： SCI

摘要： Background: Micronutrients polyphenols, tocopherols and phytosterols in rapeseed exert potential benefit to cardiovascular system, but most of these micronutrients are removed by the refining process. The aim of this study was to determine the effect of rapeseed oil fortified with these micronutrients on the atherosclerosis risk factors in rats fed a high-fat diet. Methods: The rodent diet contained 20% fat whose source was refined rapeseed oil (RRO) or fortified refined rapeseed oil with low, middle and high quantities of these micronutrients (L-, M- and H-FRRO). Forty male SD rats were divided into four groups. One group received RRO diet and other groups received L-, M-and H-FRRO diet for 10 weeks. Results: Micronutrients supplementation significantly increased plasma antioxidant defense capacities, as evaluated by the significant elevation in the activities of GPx, CAT and SOD as well as the level of GSH, and the significant decline in lipid peroxidation. These micronutrients also reduced the plasma contents of TG, TC and LDL-C and increased the ratio of HDL-C/LDL-C. In addition, in parallel with the enhancement of these micronutrients, plasma levels of IL-6 and CRP declined remarkably. Conclusion: Rapeseed oil fortified with micronutrients polyphenols, tocopherols and phytosterols may contribute to prevent atherogenesis by ameliorating plasma oxidative stress, lipid profile and inflammation.

分类号：

  • 相关文献

[1]Micronutrients-fortified rapeseed oil improves hepatic lipid accumulation and oxidative stress in rats fed a high-fat diet. Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Yang, Jin'e,Huang, Fenghong,Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Yang, Jin'e,Huang, Fenghong,Zhou, Xiaoqi,Gao, Hui,Chen, Chang,Ma, Jing,Wan, Zhengyang. 2013

[2]Optimized rapeseed oils rich in endogenous micronutrients ameliorate risk factors of atherosclerosis in high fat diet fed rats. Xu, Jiqu,Ma, Congcong,Han, Ling,Zhou, Qi,Yang, Mei,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Xu, Jiqu,Ma, Congcong,Han, Ling,Zhou, Qi,Yang, Mei,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Gao, Hui,Chen, Chang,Chen, Chang. 2014

[3]Flaxseed oil and alpha-lipoic acid combination reduces atherosclerosis risk factors in rats fed a high-fat diet. Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Yang, Jin'e,Huang, Fenghong,Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Yang, Jin'e,Huang, Fenghong,Yang, Wei. 2012

[4]A combination of flaxseed oil and astaxanthin alleviates atherosclerosis risk factors in high fat diet fed rats. Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Gao, Hui,Yang, Wei,Zhang, Li,Chen, Chang,Chen, Chang. 2014

[5]Effects of endogenous and exogenous micronutrients in rapeseed oils on the antioxidant status and lipid profile in high-fat fed rats. Deng, Qianchun,Yu, Xiao,Xu, Jiqu,Huang, Fenghong,Huang, Qingde,Liu, Changsheng,Deng, Qianchun,Yu, Xiao,Xu, Jiqu,Huang, Fenghong,Huang, Qingde,Liu, Changsheng,Wang, Lan,Ma, Fangli. 2014

[6]Butterfly pea (Clitoria ternatea) seed and petal extracts decreased HEp-2 carcinoma cell viability. Shen, Yixiao,Prinyawiwatkul, Witoon,Alonso-Marenco, Jose R.,Xu, Zhimin,Du, Liqing,Zhang, Xiumei,Zeng, Haiying.

[7]Optimized Rapeseed Oils Rich in Endogenous Micronutrients Protect High Fat Diet Fed Rats from Hepatic Lipid Accumulation and Oxidative Stress. Xu, Jiqu,Liu, Xiaoli,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Xu, Jiqu,Liu, Xiaoli,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Gao, Hui,Chen, Chang,Chen, Chang,Ma, Zhonghua. 2015

[8]A Combination of Flaxseed Oil and Astaxanthin Improves Hepatic Lipid Accumulation and Reduces Oxidative Stress in High Fat-Diet Fed Rats. Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Huang, Fenghong,Rong, Shuang,Gao, Hui,Yang, Wei,Chen, Chang,Chen, Chang,Xiao, Lingyun. 2017

[9]Influence of Microwaves Treatment of Rapeseed on Phenolic Compounds and Canolol Content. Yang, Mei,Zheng, Chang,Zhou, Qi,Liu, Changsheng,Li, Wenlin,Huang, Fenghong,Yang, Mei,Zheng, Chang,Zhou, Qi,Liu, Changsheng,Li, Wenlin.

[10]Changes in the content of canolol and total phenolics, oxidative stability of rapeseed oil during accelerated storage. Zheng, Chang,Yang, Mei,Zhou, Qi,Liu, Chang-Sheng,Huang, Feng-Hong,Zheng, Chang.

[11]Minor components and oxidative stability of cold-pressed oil from rapeseed cultivars in China. Yang, Mei,Zheng, Chang,Zhou, Qi,Huang, Fenghong,Liu, Changsheng,Wang, Hui. 2013

[12]Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Yang, Jin'e,Huang, Fenghong,Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Yang, Jin'e,Huang, Fenghong,Gao, Hui,Yang, Wei,Song, Lin,Chen, Chang. 2013

[13]Influence of Microwave Treatment of Rapeseed on Minor Components Content and Oxidative Stability of Oil. Yang, Mei,Huang, Fenghong,Liu, Changsheng,Zheng, Chang,Zhou, Qi,Wang, Hui. 2013

[14]Fatty acids, tocopherols and proanthocyanidins in bramble seeds. Xu, YH,Zhang, YP,Chen, MX,Tu, PF. 2006

[15]Effect of Industrial Chemical Refining on the Physicochemical Properties and the Bioactive Minor Components of Peanut Oil. Zhu, Minghui,Wen, Xin,Liu, Fang,Ni, Yuanying,Ma, Liyan,Li, Jingming,Zhu, Minghui,Wen, Xin,Liu, Fang,Ni, Yuanying,Zhu, Minghui,Wen, Xin,Liu, Fang,Ni, Yuanying,Zhao, Jinhong.

[16]Effect of Flaxseed Oil Fortified with Vitamin E and Phytosterols on Antioxidant Defense Capacities and Lipids Profile in Rats. Deng, Qianchun,Yu, Xiao,Xu, Jiqu,Liu, Changsheng,Huang, Fenghong,Huang, Qingde,Yang, Jine,Deng, Qianchun,Yu, Xiao,Xu, Jiqu,Liu, Changsheng,Huang, Fenghong,Huang, Qingde,Yang, Jine. 2012

[17]Metal ions accelerated phytosterol thermal degradation on Ring A & Ring B of steroid nucleus in oils. Hu, Yinzhou,Li, Maiquan,Wang, Mengmeng,Zhao, Yajing,Xu, Tao,Zhang, Liuquan,Lu, Baiyi,Hu, Yinzhou,Li, Maiquan,Wang, Mengmeng,Zhao, Yajing,Xu, Tao,Zhang, Liuquan,Lu, Baiyi,Huang, Weisu,He, Yan.

[18]Effects of dietary phytosterol concentration on performance, egg quality and cholesterol content in laying hens. Shen, Yiru,Chang, Lingling,Tong, Haibing,Shi, Shourong.

[19]Influence of dietary vitamin E supplementation on meat quality traits and gene expression related to lipid metabolism in the Beijing-you chicken. Li, W. J.,Zhao, G. P.,Chen, J. L.,Zheng, M. Q.,Wen, J..

[20]Immobilization of Candida rugosa lipase on magnetic poly(allyl glycidyl ether-co-ethylene glycol dimethacrylate) polymer microsphere for synthesis of phytosterol esters of unsaturated fatty acids. Zheng, Ming-Ming,Dong, Ling,Guo, Ping-Mei,Deng, Qian-Chun,Li, Wen-Lin,Huang, Feng-Hong,Lu, Yong,Feng, Yu-Qi. 2012

作者其他论文 更多>>

微信小程序