Genomic sequence of an avian paramyxovirus type 1 strain isolated from Muscovy duck (Cairina moschata) in China

文献类型： 外文期刊

第一作者： Shi, S. -H.

作者： Shi, S. -H.;Huang, Yu;Cheng, L. -F.;Fu, G. -H.;Chen, Z.;Peng, C. -X.;Lin, F.;Lin, J. -S.;Shi, S. -H.;Cui, S. -J.;Li, X.;Su, Jing-Liang

作者机构：

期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）

ISSN： 0304-8608

年卷期： 2011 年 156 卷 3 期

页码：

收录情况： SCI

摘要： The complete sequence of an avian paramyxovirus type 1 (APMV-1) strain, FP1/02, isolated from Muscovy duck in China, was determined. Sequence analysis indicated that the complete genome of strain FP1/02 contained 15,192 nucleotides (nt), following the rule of six. The genome contained an extra 6-nt insertion in the non-coding region of the NP gene when compared with other APMV-1 strains, such as strains La Sota and Beaudette C. The cleavage site of the F protein was R-112-R-Q-K-Ra dagger"F-117, indicating that the FP1/02 strain was virulent, but the morbidity and mortality varied with the species of duck. Genotypic analysis based on the F gene revealed that APMV-1 FP1/02 was a member of genotype VII. Phylogenetic analysis showed that the FP1/02 strain shared high identity with other APMV-1 strains such as ZJ1, SF02 and NA-1 isolated from geese.

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