Expression of Sheep CLPG in Different PRNP Genotypes

文献类型: 外文期刊

第一作者: Zhao Chun-Lin

作者: Zhao Chun-Lin;Wu Run;Liu Lei;Zhang Xiao-Li;Wang Chuan;Li Fa-Di;Wu Run

作者机构:

关键词: Sheep;CLPG;PRNP;fluorescence quantitative PCR;expression;China

期刊名称:JOURNAL OF ANIMAL AND VETERINARY ADVANCES ( 影响因子:0.365; 五年影响因子:0.359 )

ISSN: 1680-5593

年卷期: 2011 年 10 卷 22 期

页码:

收录情况: SCI

摘要: In order to investigate the possible relationship at the transcriptional level between CLPG and PRNP in sheep and the description of relationship of sheep reproductive with different PRNP genotype, the expression of CLPG gene in. different tissues and different PRNP genotypes was determined using fluorescence quantitative PCR. The results showed CLPG has a tissue-specific gene expression as CLPG gene expression in cerebellum was significantly higher than other organizations. However, genotyp specific expression was not detected in spite of the p-value in some tissues almost close to 0.05. Therefore, the researchers speculate that the expression of CLPG in different PRNP genotype may exist but the final conclusion need to be proved with the other genes which are related to growth trait in more different PRNP genotypes.

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