文献类型： 外文期刊

第一作者： Chakraborty, C.

作者： Chakraborty, C.;Shah, K. D.;Cao, W. G.;Hsu, C. H.;Wen, Z. H.;Lin, C. S.;Hsu, C. H.;Wen, Z. H.;Lin, C. S.

作者机构：

关键词： Induced pluripotent stem (iPS) cell;disease-specific iPS cell lines;drug discovery and development;toxicological studies;personalized medicine;regenerative medicine

期刊名称：CURRENT MOLECULAR MEDICINE （ 影响因子：2.222； 五年影响因子：3.084 ）

ISSN： 1566-5240

年卷期： 2010 年 10 卷 8 期

页码：

收录情况： SCI

摘要： Induced pluripotent stem (iPS) cell research has been growing a new height throughout the world due to its potentialities in medical applications. We can explore several therapeutic applications through the iPS cell research. In this review, we have first discussed the development of iPS cells, reprogramming factors, and effectiveness of iPS cells. Then we have emphasized the potential applications of iPS cells in pharmaceutical and medical sectors, such as, study of cellular mechanisms for spectrum of disease entities, disease-specific iPS cell lines for drugs discovery and development, toxicological studies of drugs development, personalized medicine, and regenerative medicine.

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