Identification of an intergenic region that is not essential for replication of goatpox virus

文献类型： 外文期刊

第一作者： Ma, Wenge

作者： Ma, Wenge;Xue, Ying;Wang, Yan;Wei, Jie;Huang, Jiong;Fu, Zihua;Ma, Wenge;Wang, Fang;Yu, Li

作者机构：

期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）

ISSN： 0304-8608

年卷期： 2010 年 155 卷 8 期

页码：

收录情况： SCI

摘要： A recombinant goatpox virus was constructed in which an enhanced green fluorescent protein gene was inserted under the control of the 11K late promoter, a guanine phosphoribosyltransferase gene was inserted under the control of the 7.5K early/late promoter, and exogenous genes were inserted into an intergenic region between loci gp_24 and gp_24.5 of the recombinant genome. Analysis of protein expression showed that LT cells infected with only the recombinant virus produced specific fluorescence. A comparative growth assay demonstrated the stability of the recombinant virus at the replication level. These results suggest that the intergenic region is not essential for replication of goatpox virus.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序