Two genotypes of H1N2 swine influenza viruses appeared among pigs in China

文献类型: 外文期刊

第一作者: Xu, Chuantian

作者: Xu, Chuantian;Zhu, Qiyun;Yang, Huanliang;Qiao, Chuanling;Chen, Yan;Xin, Xiaoguang;Chen, Hualan;Xu, Chuantian;Zhu, Qiyun;Yang, Huanliang;Qiao, Chuanling;Chen, Yan;Xin, Xiaoguang;Chen, Hualan;Xu, Chuantian;Zhang, Xiumei

作者机构:

关键词: Influenza viruses;H1N2;Genetically analyzed;Reassortment;Human;Swine

期刊名称:JOURNAL OF CLINICAL VIROLOGY ( 影响因子:3.168; 五年影响因子:3.039 )

ISSN: 1386-6532

年卷期: 2009 年 46 卷 2 期

页码:

收录情况: SCI

摘要: Background: H1N2 is one of the main subtypes of influenza, which circulates in swine all over the world. Objectives: To investigate the prevalence and genetic of H1N2 in swine of China. Study design: Two H1N2 swine influenza viruses were isolated from Tianjin and Guangdong province of China in 2004 and 2006, respectively. The molecular evolution of eight gene segments was analyzed. Result: A/Swine/Tianjin/1/2004 has low identity with A/Swine/Guangdong/2006; in the phylogenetic tree of PA gene, A/Swine/Guangdong/1/2006 and A/Swine/Guangxi/1/2006 along with the H1N2 swine isolates of North America formed a cluster: and A/Swine/Tianjin/2004 and A/Swine/Zhejiang/2004, along with the classical HIM swine isolates formed another cluster; except that NA gene of A/Swine/Tianjin/1/2004 fell into the cluster of the H3N2 human influenza virus, indicating the reassortment between H3N2 human and H1N1 swine influenza viruses. Conclusion: Two different genotypes of H1N2 appeared among pigs in China. A/swine/Guangdong/1/06 was probably from H1N2 swine influenza viruses of North America; while A/swine/Tianjin/l/04 maybe come from reassortments of classical H1N1 swine and H3N2 human viruses prevalent in North America. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved.

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