EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY

文献类型： 外文期刊

第一作者： Wang, S. Y.

作者： Wang, S. Y.;Shao, W. J.;Heng, H.;Wang, S. Y.;Liang, J. P.;Song, N. N.

作者机构：

关键词： Animals models;camel milk;glycaemia control;Rosiglitazone Maleate;Type 2 diabetes

期刊名称：JOURNAL OF CAMEL PRACTICE AND RESEARCH （ 影响因子：0.33； 五年影响因子：0.321 ）

ISSN： 0971-6777

年卷期： 2009 年 16 卷 1 期

页码：

收录情况： SCI

摘要： The efficacy of camel milk consumption as an adjunct to routine diabetes management in maintaining long-term glycaemia control in type 2 diabetes was assessed by 32 type 2 diabetes animal models and 12 patients. Thirty-two obese diabetic rats were divided into 4 groups according to method of random digits table. After 14 weeks treatment, it was observed that no significant variance compared Rosiglitazone Maleate group, Rosiglitazone Maleate+camel milk group and camel milk group with normal group. In blood glucose, blood triglycerides, blood total cholesterol, and plasma insulin there were a statistically significant change compared with diabetes group. Rosiglitazone Maleate group and Rosiglitazone Maleate+camel milk group showed significant variance in blood triglycerides (0.68+/-0.19 vs. 0.51+/-0.11 p<0.05), plasma insulin (43.52+/-18.93 vs. 26.49+/-5.60 p<0.05). Rosiglitazone Maleate+calnel milk group was more similar to normal group. Rosiglitazone Maleate+camel milk group had better treatment of type 2 diabetes animal models than Rosiglitazone Maleate group. Throughout the duration of the study, 6 randomly assigned patients underwent routine diabetes management and 6 randomly assigned patients additionally undertook daily consumption of raw camel milk (500 ml/day). In both groups, the dose of potential Rosiglitazone Maleate administration was adjusted to maintain a euglycaemic. In the group receiving camel milk, there was a significant increase in body weight (74.6+/-5.2 to 78.3+/-3.4; p<0.05) and a significant reduction in mean blood sugar (123+/-19.8 to 94.2+/-14.3; p<0.001), plasma insulin (19.76+/-2.3 to 6.2+/-0.56; p<0.001), dose of drug (4.67+/-0.91 to 1.67+/-1.3; p<0.001), blood triglycerides (1.83+/- 0.38 to 1.42+/-0.94; p<0.001), blood total cholesterol (7.7+/-1.53 to 6.1+/-0.91; p<0.001) compared to the values at the initiation of the study. Based on the results, camel milk consumption may be considered as a useful prevention and adjunct to potential Rosiglitazone Maleate administration in the management of type 2 diabetes.

分类号：

  • 相关文献

[1]MINERAL, VITAMIN AND FATTY ACID CONTENTS IN THE CAMEL MILK OF DROMEDARIES IN THE ANXI GANSU CHINA. Liang, J. P.,Wang, S. Y.,Shao, W. J.,Wen, H.,Wang, S. Y.. 2011

[2]Hypoglycemic effect of deoxynojirimycin-polysaccharide on high fat diet and streptozotocin-induced diabetic mice via regulation of hepatic glucose metabolism. Li, You-gui,Ji, Dong-feng,Zhong, Shi,Lin, Tian-bao,Lv, Zhi-qiang.

[3]Lactobacillus plantarum NCU116 fermented carrot juice evokes changes of metabolites in serum from type 2 diabetic rats. Li, Chuan,Nie, Shao-Ping,Zhu, Ke-Xue,Xiong, Tao,Xie, Ming-Yong,Li, Chuan,Zhu, Ke-Xue.

[4]Attenuated mTOR Signaling and Enhanced Glucose Homeostasis by Dietary Supplementation with Lotus Seedpod Oligomeric Procyanidins in Streptozotocin (STZ)-Induced Diabetic Mice. Li, Xiaopeng,Xie, Bijun,Sun, Zhida,Sui, Yong,Wu, Qian.

[5]A Polysaccharide from Ganoderma atrum Improves Liver Function in Type 2 Diabetic Rats via Antioxidant Action and Short-Chain Fatty Acids Excretion. Zhu, Ke-Xue,Nie, Shao-Ping,Li, Chuan,Gong, De-Ming,Xie, Ming-Yong,Zhu, Ke-Xue,Tang, Le-He,Li, Chuan,Gong, De-Ming.

[6]Dissecting the role of AMP-activated protein kinase in human diseases. Li, Jin,Wang, Fengzhong,Zhong, Liping,Zhu, Haibo,Zhu, Haibo,Zhu, Haibo,Zhu, Haibo. 2017

作者其他论文 更多>>

微信小程序