Single nucleotide polymorphism discovery of peroxisome proliferators-activated receptors gamma gene and its association with carcass traits in duck

文献类型： 外文期刊

第一作者： Wu, Yan

作者： Wu, Yan;Liu, Xiaolin;Wang, Jie;Hou, Shuisheng

作者机构：

关键词： duck (Anas platyrhynchos);PPAR-gamma;SNPs;PCR-SSCP;MAS

期刊名称：ARCHIV FUR TIERZUCHT-ARCHIVES OF ANIMAL BREEDING （ 影响因子：1.528； 五年影响因子：1.723 ）

ISSN： 0003-9438

年卷期： 2008 年 51 卷 3 期

页码：

收录情况： SCI

摘要： Peroxisome proliferators-activated receptor gamma (PPAR-gamma) is thought to play a critical role in glucose and lipid metabolism and in inflammation control. The objective of this study was to detect the single nucleotide polymorphism (SNPs) in whole coding regions of PPAR-gamma gene with single strand conformation polymorphism (SSCP) in Peking duck Z4, Z2, Hybrid and Cherry Valley duck populations. The results showed that there were two alleles and three genotypes in the experimental populations. And one novel polymorphism, a synonymous mutation G-to-T at 213 of 5th exon, was found. The birds with homozygote (TT) was highest for carcass weight, sebum weight, percentage of sebum, abdominal fat weight, percentage of abdominal fat and IMF in four duck populations; however, for breast muscular weight and carcass net weight, the birds with heterozygote (GT) was highest in them. The association analysis results showed that the SNP of the polymorphism of PPAR-gamma gene was linked with potential major loci or genes affecting some growth and fatness traits.

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