Associations between GHR and IGF-1 gene polymorphisms, and reproductive traits in Wenchang chickens
文献类型: 外文期刊
第一作者: Li, Hui-fang
作者: Li, Hui-fang;Zhu, Wen-qi;Chen, Kuan-wei;Tang, Qing-ping;Gao, Yu-shi;Wu, Xu
作者机构:
关键词: chicken;IGF-1;GHR;reproduction;single nucleotide polymorphism (SNP)
期刊名称:TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES ( 影响因子:0.581; 五年影响因子:0.78 )
ISSN: 1300-0128
年卷期: 2008 年 32 卷 4 期
页码:
收录情况: SCI
摘要: Alleles of physiological candidate genes for reproductive traits, insulin-like growth factor-1 (IGF-1), and growth hormone receptor (GHR) were assessed to determine their associations with total egg production (NE), average days of continual egg-laying (ADCE), and number of double yolk eggs (DYE) in Wenchang chickens (Chinese indigenous breed). PCR-RFLP was used for genotype identification. The frequency of restriction enzyme C1/C2 alleles in the population was 0.53 (C1) and 0.47 (C2) for IGF-1. For GHRintron 2 it was 0.06 and 0.94 for (A1) and (A2), respectively, while for GHR-intron 5 it was 0.20 (B1) and 0.80 (B2). Four significant associations were found (P < 0.05): between IGF-1 polymorphism, and NE (300 d), NE (400 d), and ADCE, and between GHR polymorphism and DYE. Two significant effects were observed: for IGF-1 and NE (300 d), and for GHR intron 2 and DYE. The current research supports the effects of GHR and IGF-1 genes on the reproductive traits of chickens.
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