Allelic variations in exon 2 of caprine MHC class II DRB3 gene in Chinese indigenous goats

文献类型： 外文期刊

第一作者： Li, Meng-Hua

作者： Li, Meng-Hua;Li, Kui;Kantanen, Juha;Feng, Zheng;Fan, Bin;Zhao, Shu-Hong

作者机构：

关键词： Chinese indigenous goat;DRB3 gene exon 2;allelic variation

期刊名称：SMALL RUMINANT RESEARCH （ 影响因子：1.611； 五年影响因子：1.813 ）

ISSN： 0921-4488

年卷期： 2006 年 66 卷 1-3 期

页码：

收录情况： SCI

摘要： Allelic variations in the second exon of caprine leukocyte antigen-DRB3 gene (CLA-DRB3*02) were investigated. A total of 459 animals from 12 Chinese indigenous goat populations were genotyped. Six alleles and 18 restriction digestion profiles were distinguished by digestion of PCR amplification product of CLA-DRB3*02 with Hael1l. The results suggested that there were significant difference (P < 0.000) in both allele frequencies and genotype frequencies of exon 2 restriction fragment length polymorphisms (RFLPs) among the breeds. The new allele CLA-DRB3*0206 was identified only in three goat populations from the three-gorge reservoir, and the breed-specific allele CLA-DRB3*0205 was merely detected in the three populations of Tibetan goat. The results also indicated that the potentially different ecological factors, such as climate, disease, topography, pasture conditions and pathogens might be account for the significantly different distribution of alleles and genotypes among the goat populations. The nucleotide and predicted amino acid sequence alignment of CLA-DRB3*02 alleles provided evidence for considerable variation among the six alleles. Phylogenetic analysis showed that the six alleles of CLA-DRB3*02 were closely related. They clustered together and were separated from the corresponding sequences of sheep and cattle, which indicated the trans-species evolution model of CLA-DRB3*02 was not present in the Chinese goat populations studied. (c) 2005 Elsevier B.V. All rights reserved.

分类号：

  • 相关文献

[1]Diversity of TNF-alpha region in Chinese domestic goats. E, G. X.,Na, R. S.,Zhao, Y. J.,Huang, Y. F.,Ma, Y. H.. 2015

[2]Diversity of Chinese indigenous goat breeds: A conservation perspective - A review. Li, MH,Li, K,Zhao, SH. 2004

[3]Characterization of a cell wall invertase gene TaCwi-A1 on common wheat chromosome 2A and development of functional markers. Dongyun Ma,Jun Yan,Zhonghu He,Ling Wu,Xianchun Xia.

[4]Allelic variation, balancing selection and positive selected sites detected from MHC class I alpha gene of olive flounder. Chen, Song-lin,Xu, Tian-jun,Sun, Yue-na. 2010

[5]Quantitative Trait Loci Associated with Drought Tolerance in Brachypodium distachyon. Jiang, Yiwei,Pei, Zhongyou,Liu, Huifen,Jiang, Yiwei,Zhao, Xiongwei,Wang, Xicheng,Yu, Xiaoqing,Zhao, Xiongwei,Luo, Na,Garvin, David F.,Garvin, David F.. 2017

[6]Characterization of Tamyb10 allelic variants and development of STS marker for pre-harvest sprouting resistance in Chinese bread wheat. Wang, Y.,Wang, X. L.,Meng, J. Y.,Yang, Y.,Zhang, Y. J.,He, Z. H..

[7]Comparison of amylopectin structure and activities of key starch synthesis enzymes in the grains of rice single-segment substitution lines with different Wx alleles. Teng, Bin,Zhang, Ying,Wu, Jingde,Li, Zefu,Luo, Zhixiang,Yang, Jianbo,Zhang, Chen.

[8]Detection of allelic variation at the Wx locus with single-segment substitution lines in rice (Oryza sativa L.). Teng, Bin,Zeng, Ruizhen,Wang, Yicun,Liu, Ziqiang,Zhang, Zemin,Zhu, Haitao,Ding, Xiaohua,Li, Wentao,Zhang, Guiquan,Teng, Bin,Zeng, Ruizhen,Liu, Ziqiang,Zhang, Zemin,Zhang, Guiquan. 2012

[9]DEVELOPMENT OF STS MARKERS FOR WAXY GENE ALLELIC VARIATION IDENTIFICATION IN FOXTAIL MILLET. Jia, X. P.,Dong, P. H.,Yu, F. Y.,Quan, J. Z.,Bai, H.,Dong, Z. P.. 2015

[10]Characterization of a Cry1Ac toxin-binding alkaline phosphatase in the midgut from Helicoverpa armigera (Hubner) larvae. Wu, Kongming,Liu, Chenxi,Gao, Yulin,Ning, Changming,Gao, Xiwu,Jurat-Fuentes, Juan Luis.

[11]Novel alleles among soybean Bowman-Birk proteinase inhibitor gene families. Wang YuePing,Qiu LiJuan,Wang YuePing,Chen XiongTing. 2008

[12]Characterization of a New Pm2 Allele Conferring Powdery Mildew Resistance in the Wheat Germplasm Line FG-1. Ma, Pengtao,Xu, Hongxng,Zhang, Hongxia,Han, Guohao,Xu, Yunfeng,Zhang, Xiaotian,An, Diaoguo,Li, Lihui,Fu, Xiaoyi. 2016

[13]Allelic variation of a soluble acid invertase gene (SAI-1) and development of a functional marker in sweet sorghum [Sorghum bicolor (L.) Moench]. Liu, Yang,Nie, Yuan-Dong,Han, Fen-Xia,Zhao, Xiang-Na,Dun, Bao-Qing,Lu, Ming,Li, Gui-Ying,Liu, Yang. 2014

[14]Natural allelic variations of TCS1 play a crucial role in caffeine biosynthesis of tea plant and its related species. Jin, Ji-Qiang,Yao, Ming-Zhe,Ma, Chun-Lei,Ma, Jian-Qiang,Chen, Liang.

[15]Assessing and broadening genetic diversity of a rapeseed germplasm collection. Wu, Jinfeng,Li, Feng,Xu, Kun,Cao, Guizhen,Chen, Biyun,Yan, Cuixin,Wang, Nian,Qiao, Jiangwei,Li, Jun,Li, Hao,Zhang, Tianyao,Song, Weiling,Wu, Xiaoming.

[16]Allelic Variation at the Glu-D3 Locus in Chinese Bread Wheat and Effects on Dough Properties, Pan Bread and Noodle Qualities. Liu, L.,He, Z. H.,Xia, X. C.,He, Z. H.,Ma, W. J.,Liu, J. J.,Pena, R. J..

[17]Single nucleotide polymorphism of CACNA2D1 gene and its association with milk somatic cell score in cattle. Yuan, Zheng Rong,Li, Jiao,Liu, Li,Zhang, Lu Pei,Zhang, Li Min,Chen, Cui,Chen, Xiao Jie,Gao, Xue,Li, Jun Ya,Chen, Jin Bao,Gao, Hui Jiang,Xu, Shang Zhong.

[18]Haplotypic Structure and Allelic Variation of rab17, an ABA-Responsive Gene, in a Mini Core Set of Chinese Diversified Maize Inbred Lines. Yu Yong-tao,Wang Rong-huan,Shi Yun-su,Song Yan-chun,Wang Tian-yu,Li Yu,Yu Yong-tao. 2010

[19]Cloning and allelic variation of two novel catalase genes (SoCAT-1 and SsCAT-1) in Saccharum officinarum L. and Saccharum spontaneum L.. Liu, Yang,Yao, Yanli,Hu, Xiaowen,Xing, Shulian,Xu, Lei,Liu, Yang.

[20]Novel DNA variations to characterize low molecular weight glutenin Glu-D3 genes and develop STS markers in common wheat. Zhao, X. L.,Xia, X. C.,He, Z. H.,Lei, Z. S.,Appels, R.,Yang, Y.,Sun, Q. X.,Ma, W..

作者其他论文 更多>>
  • EXPERT expands prime editing efficiency and range of large fragment edits

    作者：Xiong, Youcai;Su, Yinyu;He, Ruigao;Han, Xiaosong;Li, Sheng;Liu, Minghuan;Xi, Xiaoning;Liu, Zijia;Wang, Heng;Xie, Shengsong;Xu, Xuewen;Li, Xinyun;Zhao, Shuhong;Ruan, Jinxue;Xiong, Youcai;Su, Yinyu;He, Ruigao;Han, Xiaosong;Li, Sheng;Liu, Minghuan;Xi, Xiaoning;Liu, Zijia;Wang, Heng;Xie, Shengsong;Xu, Xuewen;Li, Xinyun;Zhao, Shuhong;Ruan, Jinxue;Han, Xiaosong;Zhao, Shuhong;Xie, Shengsong;Xu, Xuewen;Li, Xinyun;Zhao, Shuhong;Xie, Shengsong;Xu, Xuewen;Li, Xinyun;Zhao, Shuhong;Li, Kui;Zhang, Jifeng;Xu, Jie

    关键词：

  • Telomere-to-telomere sheep genome assembly identifies variants associated with wool fineness

    作者：Luo, Ling-Yun;Wu, Hui;Zhang, Ya-Hui;Huang, Jia-Hui;Mo, Dong-Xin;Li, Meng-Hua;Luo, Ling-Yun;Wu, Hui;Zhang, Ya-Hui;Huang, Jia-Hui;Mo, Dong-Xin;Li, Meng-Hua;Luo, Ling-Yun;Wu, Hui;Zhang, Ya-Hui;Huang, Jia-Hui;Mo, Dong-Xin;Li, Meng-Hua;Zhao, Li-Ming;Wang, Wei-Min;Zhao, Li-Ming;Wang, Wei-Min;Zhao, Li-Ming;Wang, Wei-Min;Zhao, Li-Ming;Wang, Wei-Min;Liu, Qiu-Yue;Wang, Hai-Tao;Eer, He-Hua;Zhang, Lian-Quan;Chen, Hai-Liang;Jia, Shan-Gang

    关键词：

  • Genetic advancements and future directions in ruminant livestock breeding: from reference genomes to multiomics innovations

    作者：Xu, Songsong;Liu, Jiaxin;Feng, Xueyan;Yu, Yi;Yang, Ji;Wang, Yachun;Yu, Ying;Li, Menghua;Xu, Songsong;Liu, Jiaxin;Feng, Xueyan;Yu, Yi;Yang, Ji;Wang, Yachun;Yu, Ying;Li, Menghua;Xu, Songsong;Liu, Jiaxin;Feng, Xueyan;Yu, Yi;Yang, Ji;Wang, Yachun;Yu, Ying;Li, Menghua;Akhatayeva, Zhanerke;Badaoui, Bouabid;Esmailizadeh, Ali;Kantanen, Juha;Amills, Marcel;Amills, Marcel;Lenstra, Johannes A.;Johansson, Anna M.;Coltman, David W.;Coltman, David W.;Liu, George E.;Curik, Ino;Curik, Ino;Orozco-terWengel, Pablo;Paiva, Samuel R.;Zinovieva, Natalia A.;Zhang, Linwei;Liu, Zhihong;Li, Menghua

    关键词：ruminant livestock; genomics; domestication; genetic improvement

  • Genome-Wide Silencer Screening Reveals Key Silencer Modulating Reprogramming Efficiency in Mouse Induced Pluripotent Stem Cells

    作者：Zhu, Xiusheng;Huang, Lei;Li, Guoli;Deng, Biao;Wang, Xiaoxiao;Yang, Hu;Zhang, Yuanyuan;Wen, Qiuhan;Wang, Chao;Zhang, Jingshu;Li, Kui;Liu, Yuwen;Deng, Biao;Deng, Biao;Zhao, Yunxiang

    关键词：cis-regulatory elements; high-throughput; iPSCs; silencer; Ss-STARR-seq

  • Transcriptome analysis reveals no obvious unintended effects in the spleen of CRISPR/Cas9-mediated CD163 and pAPN double-knockout pigs

    作者：Liu, Zhi-Guo;Wang, Nan;Wang, Wan-Jie;Chi, Shun-Shun;Nie, Yu-Xin;Yuan, Mao-Sha;Sun, Ya-Ru;Mu, Yu-Lian;Li, Kui;Wang, Nan;Huang, Lei;Chi, Shun-Shun;Li, Kui

    关键词：CD163; pAPN; Double-knockout; Gene editing; Pig; Spleen; Unintended effects; Transcriptomics

  • Integrating large-scale meta-GWAS and PigGTEx resources to decipher the genetic basis of 232 complex traits in pigs

    作者：Xu, Zhiting;Lin, Qing;Cai, Xiaodian;Zhong, Zhanming;Teng, Jinyan;Zeng, Haonan;Gao, Yahui;Wei, Chen;Zhou, Jun;Zhang, Wenjing;Zhang, Xiaoke;Shi, Shaolei;Wu, Jun;Diao, Shuqi;Liu, Yuqiang;Pan, Xiangchun;Feng, Xueyan;Liu, Ruiqi;Su, Zhanqin;Chang, Chengjie;Zhu, Qianghui;Wu, Yuwei;Zhang, Hao;Yuan, Xiaolong;Li, Jiaqi;Zhang, Zhe;Li, Bingjie;Gao, Yahui;Liu, George E.;Gao, Yahui;Ma, Li;Cai, Zexi;Bai, Zhonghao;Su, Guosheng;Sahana, Goutam;Lund, Mogens Sando;Fang, Lingzhao;Wang, Xiaoqing;Shi, Liangyu;Zhao, Fuping;Wang, Xue;Wang, Yi;Zhang, Zipeng;Ding, Xiangdong;Lin, Yu;Tang, Guoqing;Li, Mingzhou;Li, Xuewei;Liu, Shuli;Yin, Hongwei;Bai, Lijing;Li, Kui;Zhou, Zhongyin;Wang, Qishan;Pan, Yuchun;Xu, Zhong;Peng, Xianwen;Mei, Shuqi;Mo, Delin;Liu, Xiaohong;Chen, Yaosheng;Liu, Yang;Xiang, Ruidong;Xiang, Ruidong;Shen, Xia;Shen, Xia;Shen, Xia;Li, Pinghua;Huang, Ruihua;Li, Pinghua;Huang, Ruihua;Ballester, Maria;Crespo-Piazuelo, Daniel;Amills, Marcel;Clop, Alex;Amills, Marcel;Karlskov-Mortensen, Peter;Fredholm, Merete;Zhang, Qin;Zhao, Yunxiang

    关键词：pig; meta-GWAS; PigGTEx; molQTL; complex traits

  • Multi-dimensional annotation of porcine variants using genomic and epigenomic features in pigs

    作者：Yin, Hongwei;Yang, Liu;Zhao, Qianyi;Yao, Wenye;Bai, Lijing;Li, Kui;Fang, Lingzhao;Yao, Wenye;Groenen, Martien A. M.;Madsen, Ole;Teng, Jinyan;Gao, Yahui;Xu, Zhiting;Lin, Qing;Diao, Shuqi;Li, Jiaqi;Zhang, Zhe;Zhou, Huaijun;Guan, Dailu;Liu, Xiaohong;Zhao, Fuping;Zhou, Zhongyin;Wang, Qishan

    关键词：Genomic variants; Gene expression and splicing; Complex traits; Non-coding regions; Epigenome

微信小程序