Identification of a natural recombinant transmissible gastroenteritis virus between Purdue and Miller clusters in China

文献类型： 外文期刊

第一作者： Zhang, Xin

作者： Zhang, Xin;Zhu, Yunnuan;Zhu, Xiangdong;Shi, Hongyan;Chen, Jianfei;Shi, Da;Yuan, Jing;Cao, Liyan;Liu, Jianbo;Dong, Hui;Jing, Zhaoyang;Zhang, Jialin;Wang, Xiaobo;Feng, Li;Dong, Hui

作者机构：

关键词： identification;natural recombinant;transmissible gastroenteritis virus

期刊名称：EMERGING MICROBES & INFECTIONS （ 影响因子：7.163； 五年影响因子：7.329 ）

ISSN： 2222-1751

年卷期： 2017 年 6 卷

页码：

收录情况： SCI

摘要： Transmissible gastroenteritis virus (TGEV) is an infective coronavirus (CoV) that causes diarrhea-related morbidity and mortality in piglets. For the first time, a natural recombination strain of a TGEV Anhui Hefei (AHHF) virus between the Purdue and the Miller clusters was isolated from the small intestine content of piglets in China. A phylogenetic tree based on a complete genome sequence placed the TGEV AHHF strain between the Purdue and the Miller clusters. The results of a computational analysis of recombination showed that the TGEV AHHF strain is a natural recombinant strain between these clusters. Two breakpoints located in the open reading frame 1a (ORF1a) and spike (S) genes were identified. The pathogenicity of the TGEV AHHF strain was evaluated in piglets, and the results show that TGEV AHHF is an enteric pathogenic strain. These results provide valuable information about the recombination and evolution of CoVs and will facilitate future investigations of the molecular pathogenesis of TGEV.

分类号：

  • 相关文献

[1]Analysis of the gene 3 region sequences of Chinese field strains of Transmissible gastroenteritis virus. Wang, C. B.,Feng, L.,Chen, J. F.,Shi, H. Y.,Qiu, H. J.,Xue, F.,Zhu, Y. M.,Liu, S. W.. 2010

[2]Identification of the interaction between vimentin and nucleocapsid protein of transmissible gastroenteritis virus. Zhang, Xin,Shi, HongYan,Chen, JianFei,Shi, Da,Dong, Hui,Feng, Li.

[3]ORF3a deletion in field strains of porcine-transmissible gastroenteritis virus in China: A hint of association with porcine respiratory coronavirus. Zhang, X.,Zhu, Y.,Zhu, X.,Chen, J.,Shi, H.,Shi, D.,Dong, H.,Feng, L.,Dong, H..

[4]In vitro inhibition of transmissible gastroenteritis coronavirus replication in swine testicular cells by short hairpin RNAs targeting the ORF 7 gene. He, Lei,Zhang, Yan-ming,Dong, Ling-juan,Cheng, Min,Wang, Jing,Tang, Qing-hai,Wang, Gang,Tang, Qing-hai. 2012

[5]Molecular characterization of a Chinese vaccine strain of transmissible gastroenteritis virus: mutations that may contribute to attenuation. Wang, Chengbao,Chen, Jianfei,Shi, Hongyan,Qiu, Huaji,Xue, Fei,Liu, Changming,Zhu, Yuanmao,Liu, Shengwang,Feng, Li,Almazan, Fernando,Enjuanes, Luis. 2010

[6]Rapid differentiation of vaccine strain and Chinese field strains of transmissible gastroenteritis virus by restriction fragment length polymorphism of the N gene. Wang, Chengbao,Chen, Jianfei,Shi, Hongyan,Qiu, Hua-Ji,Xue, Fei,Liu, Shengwang,Liu, Changming,Zhu, Yuanmao,Feng, Li,Almazan, Fernando,Enjuanes, Luis. 2010

[7]IL-22 suppresses the infection of porcine enteric coronaviruses and rotavirus by activating STAT3 signal pathway. Xue, Mei,Fu, Fang,Li, Lin,Ma, Yanlong,Shi, Hongyan,Zhang, Jiaoer,Feng, Li,Liu, Pinghuang,Zhao, Jing,Ying, Lan.

[8]QTL mapping for fiber quality traits across multiple generations and environments in upland cotton. Fu-Ding Sun,Jian-Hong Zhang,Shu-Fang Wang,Wan-Kui Gong,Yu-Zhen Shi,Ai-Ying Liu,Jun-Wen Li,Ju-Wu Gong,Hai-Hong Shang,You-Lu Yuan.

[9]Identification of Antifungal Substance (Iturin A(2)) Produced by Bacillus subtilis B47 and Its Effect on Southern Corn Leaf Blight. Li Qi-qin,Yuan Gao-qing,Lin Wei,Ye Yun-feng,Miao Jian-hua,Fu Gang. 2012

[10]CROP DISCRIMINATION IN SHANDONG PROVINCE BASED ON PHENOLOGY ANALYSIS OF MULTI-YEAR TIME SERIES. Xu, Qingyun,Yang, Guijun,Long, Huiling,Xu, Qingyun,Wang, Chongchang,Xu, Qingyun,Wang, Chongchang,Xu, Qingyun,Yang, Guijun,Long, Huiling. 2013

[11]ITS sequence-based identification and utilization evaluation of "Nanjiang" (Lonicera similis Hemsl.), a local cultivar in Sichuan, China. Chen, Xiaomin,Bai, Linhan,Hu, Shangqin,Huang, Lulin,Yang, Xiao,Tong, Wen. 2012

[12]Identification and molecular survey of Borrelia burgdorferi sensu lato in sika deer (Cervus nippon) from Jilin Province, north-eastern China. Zhai, Bintao,Zeng, Qiaoying,Zhai, Bintao,Niu, Qingli,Yang, Jifei,Liu, Zhijie,Liu, Junlong,Yin, Hong,Yin, Hong. 2017

[13]Biotechnological advances in the diagnosis, species differentiation and phylogenetic analysis of Schistosoma spp.. Zhao, Guang-Hui,Li, Juan,Li, Xiao-Yan,Zhu, Xing-Quan,Zhao, Guang-Hui,Li, Juan,Lin, Rui-Qing,Blair, David,Li, Xiao-Yan,Elsheikha, Hany M.,Zou, Feng-Cai,Zhu, Xing-Quan. 2012

[14]IDENTIFICATION OF EXPRESSED RESISTANCE GENE ANALOGS (RGA) AND DEVELOPMENT OF RGA-SSR MARKERS IN TOBACCO. Yuan, Qinghua,Xie, Ruihong,Zhang, Zhenchen,Ma, Zhuwen,Li, Jiqin,Li, Shuling,Chen, Junbiao,Lu, Yonghua. 2015

[15]Reovirus infection emerged in cultured channel catfish, Ictalurus punctatus, in China. Zeng, Lingbing,Luo, Xiaosong,Fan, Yuding,Xu, Jin,Wang, Yao,Gong, Shiyuan. 2013

[16]Isolation, Identification, and Detection, of the Virulence Factor of Vibrio cholerae in Grass Carp. Teng, Tao,Liang, Liguo,Xie, Jun. 2015

[17]Identification of Plant-Pathogenic Fungi Using Fourier Transform Infrared Spectroscopy Combined with Chemometric Analyses. Chai A-li,Zhu Fa-di,Shi Yan-xia,Xie Xue-wen,Li Bao-ju,Wang Yi-kai. 2016

[18]Cyprinid herpesvirus 2 infection emerged in cultured gibel carp, Carassius auratus gibelio in China. Xu, Jin,Zeng, Lingbing,Zhang, Hui,Zhou, Yong,Ma, Jie,Fan, Yuding. 2013

[19]Isolation and Identification of a Newly Isolated Alternaria sp ND-16 and Characterization of Xylanase. Li, Yin,Liu, Zhiqiang,Liu, Zhiqiang,Li, Geng,Cui, Fengjie,Ping, Lifeng,Qiu, Chongyan,Yan, Lijiao,Yan, Lijiao. 2009

[20]Metabolomics Investigation of an Association of Induced Features and Corresponding Fungus during the Co-culture of Trametes versicolor and Ganoderma applanatum. Xu, Xiao-Yan,Shen, Xiao-Ting,Yuan, Xiao-Jie,Zhu, Li-Ping,Yang, Song,Zhou, Yuan-Ming,Fan, Huan,Du, Feng-Yu,Sadilek, Martin,Yang, Jie,Qiao, Bin,Yang, Song. 2018

作者其他论文 更多>>

微信小程序