Research and development on lactoferrin and its derivatives in China from 2011-2015
文献类型: 外文期刊
第一作者: Wang, Xiao
作者: Wang, Xiao;Wang, Xiumin;Hao, Ya;Teng, Da;Wang, Jianhua;Wang, Xiao;Wang, Xiumin;Hao, Ya;Teng, Da;Wang, Jianhua
作者机构:
关键词: lactoferrin;lactoferricin;biological function;expression;application
期刊名称:BIOCHEMISTRY AND CELL BIOLOGY ( 影响因子:3.626; 五年影响因子:3.178 )
ISSN: 0829-8211
年卷期: 2017 年 95 卷 1 期
页码:
收录情况: SCI
摘要: Lactoferrin (Lf), a multifunctional glycoprotein, is an important antimicrobial and immune regulatory protein present in neutrophils and most exocrine secretions of mammals. Lactoferricin (Lfcin) is located in the N-terminal region of this protein. In this review, the current state of research into Lf and Lfcin in China is described. Searching with HistCite software in Web Sci located 118 papers published by Chinese researchers from 2011-2015, making China one of the top 3 producers of Lf research and development in the world. The biological functions of Lf and Lfcin are discussed, including antibacterial, antiviral, antifungal, anticarcinogenic, and anti-inflammatory activities; targeted drug delivery, induction of neurocyte, osteoblast, and tenocyte growth, and possible mechanisms of action. The preparation and heterologous expression of Lf in animals, bacteria, and yeast are discussed in detail. Five Lf-related food additive factories and 9 Lf-related health food production companies are certified by the China Food and Drug Administration (CFDA). The latest progress in the generation of transgenic livestock in China, the safety of the use of transgenic animals, and future prospects for the uses of Lf and Lfcin are also covered.
分类号:
- 相关文献
作者其他论文 更多>>
-
Analysis of the steady-state concentrations of reactive species and their role in contaminant degradation by the iron-biochar/persulfate advanced oxidation process: Comparison of probe compound and quenching agent methods
作者:Meng, Xukun;Peng, Guilong;Yan, Yuting;Wang, Xiao;Zhu, Jiangwei;Belver, Carolina;Gong, Wenwen;Blaney, Lee;Peng, Guilong
关键词:Reactive species; Persulfate; Steady-state concentration; Iron-biochar; Advanced oxidation processes
-
Effect of land use on soil nematode community composition and co-occurrence network relationship
作者:Liu, Xiaotong;Tian, Yijia;Wang, Xiao;Liang, Wenju;Zhang, Xiaoke;Liang, Siwei;Liu, Xiaotong;Tian, Yijia;Wang, Xiao;Liang, Wenju;Zhang, Xiaoke
关键词:soil nematode; trophic groups; community composition; co-occurrence network; land use
-
Combined treatment of rice bran by solid-state fermentation and extrusion: Effect of processing sequence and microbial strains
作者:Wu, Songheng;Zhang, Yi;Chen, Bingjie;Wang, Xiao;Qiao, Yongjin;Qiao, Yongjin;Chen, Jianyu
关键词:Aspergillus oryzae; Lactiplantibacillus plantarum; Neurospora sitophila; Treatment order; Bioactive components; arabinoxylan
-
Genome-wide survey reveals the genetic background of Xinjiang Brown cattle in China
作者:Wang, Xiao;Liu, Wujun;Wang, Xiao;Gao, Liang;Ma, Zhen;Yuan, Lixin;Ye, Zhibing;Cui, Fanrong;Yan, Xiangmin;Guo, Xiaoping
关键词:Xinjiang Brown cattle; specific-locus amplified fragment-sequencing; genetic structure; genetic diversity; candidate genes; ancestry proportion
-
Bacillus subtilis Simultaneously Detoxified Aflatoxin B1 and Zearalenone
作者:Wu, Jianwen;Li, Huanrong;Wu, Jianwen;Wang, Zhenlong;An, Wei;Gao, Boquan;Li, Chunxiao;Han, Bing;Tao, Hui;Wang, Jinquan;Wang, Xiumin;Wu, Jianwen;Wang, Zhenlong;An, Wei;Gao, Boquan;Li, Chunxiao;Han, Bing;Tao, Hui;Wang, Jinquan;Wang, Xiumin
关键词:mycotoxins; degradation; aflatoxin; zearalenone; Bacillus subtilis; active components; feed
-
Identification and Validation of Magnolol Biosynthesis Genes in Magnolia officinalis
作者:Yang, Yue;Li, Zihe;Zong, Hang;Li, Zhenzhu;Wang, Wen;Liu, Shimeng;Du, Qiuhui;Wu, Hao;Wang, Xiao;Huang, Lihui;Lai, Changlong;Chen, Xianqing;Zhang, Meide
关键词:Magnolia officinalis; transcripts; in vitro; magnolol synthesis; enzyme activity
-
Polylactic Glycolic Acid-Mediated Delivery of Plectasin Derivative NZ2114 in Staphylococcus epidermidis Biofilms
作者:Ma, Xuanxuan;Yang, Na;Mao, Ruoyu;Hao, Ya;Teng, Da;Wang, Jianhua;Ma, Xuanxuan;Huang, Yinhua;Ma, Xuanxuan;Yang, Na;Mao, Ruoyu;Hao, Ya;Teng, Da;Wang, Jianhua
关键词:antimicrobial peptide NZ2114; drug delivery system; nanoparticles; PLGA; Staphylococcus epidermidis; biofilms