Biological effects of trans fatty acids and their possible roles in the lipid rafts in apoptosis regulation
文献类型: 外文期刊
第一作者: Qiu, Bin
作者: Qiu, Bin;Wang, Qing;Liu, Wei;Xu, Tong-Cheng;Liu, Li-Na;Zong, Ai-Zhen;Jia, Min;Du, Fang-Ling;Qiu, Bin;Wang, Qing;Liu, Wei;Xu, Tong-Cheng;Liu, Li-Na;Zong, Ai-Zhen;Jia, Min;Du, Fang-Ling;Qiu, Bin;Wang, Qing;Liu, Wei;Xu, Tong-Cheng;Liu, Li-Na;Zong, Ai-Zhen;Jia, Min;Du, Fang-Ling;Li, Jing
作者机构:
关键词: Apoptosis; lipid rafts; structure; trans fatty acid
期刊名称:CELL BIOLOGY INTERNATIONAL ( 影响因子:3.612; 五年影响因子:3.055 )
ISSN: 1065-6995
年卷期: 2018 年 42 卷 8 期
页码:
收录情况: SCI
摘要: A large number of recent studies are focused on evaluating the mechanism of action of trans fatty acids (TFAs) on the progression of apoptosis. A strong positive association has been reported between TFA and coronary heart disease (CHD), obesity and nonalcoholic steatohepatitis and so on. The present study reviewed the biological effects of trans fatty acids (TFA) and their possible roles in lipid rafts in regulating apoptosis. The following aspects of TFA were included: the research about TFA and diseases affecting serum lipid levels, inducing system inflammation and immune response, and the correlation between TFA and apoptosis. The primary purpose of the review article was to comprehensively evaluate the potential correlation between lipid rafts and apoptosis induced by different structures of TFA and provide some new research progress and future directions about it.
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