Dietary leucine modulates growth performance, Nrf2 antioxidant signaling pathway and immune response of juvenile blunt snout bream (Megalobrama amblycephala)

文献类型: 外文期刊

第一作者: Liang, Hualiang

作者: Liang, Hualiang;Mokrani, Ahmed;Ji, Ke;Ge, Xianping;Ren, Mingchun;Xie, Jun;Liu, Bo;Ge, Xianping;Ren, Mingchun;Xie, Jun;Liu, Bo;Xi, Bingwen;Zhou, Qunlan

作者机构:

关键词: Blunt snout bream (Megalobrama amblycephala);leucine;Growth performance;Nrf2 antioxidant signaling pathway;Immune response

期刊名称:FISH & SHELLFISH IMMUNOLOGY ( 影响因子:4.581; 五年影响因子:4.851 )

ISSN: 1050-4648

年卷期: 2018 年 73 卷

页码:

收录情况: SCI

摘要: The present study assessed the effects of dietary leucine on growth performance, antioxidant status and immunity in juvenile blunt snout bream. Fish were fed six practical diets of graded leucine levels ranging from 0.90% to 2.94% of dry basis for 8 weeks. Trail results showed that compared to control group (0.90%), 1.72% dietary leucine level significantly improved final weight (FW), weight gain rate (WG) and specific growth rate (SGR), and significantly lowered feed conversion ratio (FCR). Based on WG and SGR, the optimal dietary leucine level was obtained at 1.40% and 1.56%, respectively. Whole body crude lipid and protein contents were improved with increasing dietary leucine up to 2.14% and thereafter showed a downward trend, while whole body moisture content showed a converse trend. No significant change was found in whole body ash content. 1.72% dietary leucine level significantly improved the antioxidant capacity of fish by regulating the plasma superoxide dismutase (SOD) activity, glutathione peroxidase (GPx) activity, total antioxidant capacity (T-AOC) activity, catalase (CAT) activity, aspartate aminotransferase (AST) activities and malondialdehyde (MDA) content, furthermore, 1.72% dietary leucine level also significantly improved the antioxidant genes expressions of associated with Nrf2 signaling pathway by regulating heme oxygenase-1 (HO-1), GPx, copperezinc superoxide dismutase (Cu/Zn-SOD), manganese superoxide dismutase (Mn-SOD), 2.14% dietary leucine levels also significantly improved glutathione transferase (GST) mRNA level. Dietary leucine levels significantly affected plasma immunity parameters such as the contents of plasma complement component 3 (C3), immunoglobulin M (IgM) and lowered the hepatopancreas genes expressions of pro-inflammatory factor by regulating interleukin 1 beta (IL-1 beta), interleukin 8 (IL-8) and tumour necrosis factor-alpha (TNF-alpha) mRNA levels. The present study indicated that optimal dietary leucine level plays an important role in improving growth, enhancing antioxidant and immune status to maintain the health in juvenile blunt snout bream.

分类号:

  • 相关文献

[1]Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala). Habte-Tsion, Habte-Michael,Ren, Mingchun,Liu, Bo,Ge, Xianping,Xie, Jun,Ren, Mingchun,Liu, Bo,Ge, Xianping,Xie, Jun,Chen, Ruli,Habte-Tsion, Habte-Michael.

[2]Dietary leucine level affects growth performance, whole body composition, plasma parameters and relative expression of TOR and TNF-alpha in juvenile blunt snout bream, Megalobrama amblycephala. Ren, Mingchun,Liu, Bo,Miao, Linghong,Ge, Xianping,Xie, Jun,Zhou, Qunlan,Pan, Liangkun,Ren, Mingchun,Habte-Tsion, Habte-Michael,Liu, Bo,Miao, Linghong,Ge, Xianping,Xie, Jun,Liang, Hualiang,Zhou, Qunlan.

[3]Effects of dietary carbohydrate source on growth performance, diet digestibility and liver glucose enzyme activity in blunt snout bream, Megalobrama amblycephala. Ren, Mingchun,Xie, Jun,Liu, Bo,Zhou, Qunlan,Ge, Xianping,Pan, Liangkun,Chen, Ruli,Ren, Mingchun,Habte-Tsion, Habte-Michael,Xie, Jun,Liu, Bo,Ge, Xianping.

[4]Dietary methionine requirement of juvenile blunt snout bream (Megalobrama amblycephala) at a constant dietary cystine level. Liao, Y. J.,Liu, B.,Cui, H. H.,Xie, J.,Ge, X. P.,Ren, M. C.,Liu, B.,Sun, S. M.,Xie, J.,Zhou, Q. L.,Pan, L. K.,Chen, R. L.,Ge, X. P..

[5]Effects of dietary folic acid on the growth, digestive enzyme activity, immune response and antioxidant enzyme activity of blunt snout bream (Megalobrama amblycephala) fingerling. Sesay, Daniella Fatmata,Habte-Tsion, Habte-Michael,Zhou, Qunlan,Ren, Mingchun,Xie, Jun,Liu, Bo,Zhou, Qunlan,Ren, Mingchun,Xie, Jun,Liu, Bo,Chen, Ruli,Pan, Liangkun.

[6]Effect of biofloc technology on growth, digestive enzyme activity, hematology, and immune response of genetically improved farmed tilapia (Oreochromis niloticus). Long, Lina,Yang, Jing,Guan, Chongwu,Wu, Fan,Li, Yuan.

[7]Effect of guava leaves on growth and the non-specific immune response of Penaeus monodon. Yin, Xiao-Li,Li, Zhuo-Jia,Yang, Keng,Lin, Hei-Zhao,Guo, Zhi-Xun,Yin, Xiao-Li.

[8]Effect of Dietary Marine Red Yeast Rhodotorula mucilaginosa on the Growth Performance, and also Non-Specific Immune Responses of Juvenile Golden Pompano Trachinotus Ovatus when Challenged with Vibrio Harveyi. Zhou, Chuanpeng,Lin, Heizhao,Xia, Dongmei,Yang, Keng,Yang, Yingying,Huang, Zhong,WeiYu,Zhou, Chuanpeng,Lin, Heizhao,Xia, Dongmei,Yang, Keng,Yang, Yingying,Huang, Zhong,WeiYu,Lin, Heizhao,Huang, Zhong,WeiYu. 2016

[9]Effects of probiotics dietary supplementation on growth performance; innate immunity and digestive enzymes of silver pomfret, Pampas argenteus. Gao, Quanxin,Xiao, Changfeng,Min, Minghua,Zhang, Chenjie,Peng, Shiming,Shi, Zhaohong,Xiao, Changfeng.

[10]Growth performance and immune responses of gibel carp, Carassius auratus gibelio, fed with graded level of rare earth-chitosan chelate. Zhou, Qun-lan,Xie, Jun,Ge, Xian-ping,Liu, Bo,Ren, Mingchun,Zhou, Qun-lan,Habte-Tsion, H. Michael.

[11]Effects of dietary glycyl-glutamine on growth performance, small intestinal integrity, and immune responses of weaning piglets challenged with lipopolysaccharide. Jiang, Z. Y.,Lin, Y. C.,Ma, X. Y.,Zheng, C. T.,Zhou, G. L.,Chen, F.,Zou, S. T.,Sun, L. H..

[12]Effect of dietary astaxanthin on the growth performance, non-specific immunity, and antioxidant capacity of pufferfish (Takifugu obscurus) under high temperature stress. Cheng, Chang-Hong,Guo, Zhi-Xun,Cheng, Chang-Hong,Guo, Zhi-Xun,Ye, Chao-Xia,Wang, An-Li,Ye, Chao-Xia,Wang, An-Li. 2018

[13]Enhancement of immune responses to infectious bursal disease vaccine by supplement of an extract made from Momordica cochinchinensis (Lour.) Spreng. seeds. Rajput, Z. I.,Xiao, C. W.,Hu, S. H.,Rajput, Z. I.,Xiao, C. W.,Habib, M.,Soomro, N. A..

[14]Activation of mammalian target of rapamycin signaling in skeletal muscle of neonatal chicks: Effects of dietary leucine and age. Deng, Huiling,Zheng, Aijuan,Liu, Guohua,Chang, Wenhuan,Zhang, Shu,Cai, Huiyi. 2014

[15]Acetolactate Synthase Gene Pro line (197) Mutations Confer Tribenuron-Methyl Resistance in Flixweed (Descurainia sophia) Populations from China. Zhang, Chao Xian,Wei, Shou Hui,Li, Xiang Ju,Cui, Hai Lan,Zhang, Chao Xian,Wei, Shou Hui,Li, Xiang Ju,Zhang, Hong Jun,Zhang, Yan Qiu,Wang, Gui Qi.

[16]Leucine and histidine independently regulate milk protein synthesis in bovine mammary epithelial cells via mTOR signaling pathway. Gao, Hai-na,Hu, Han,Zheng, Nan,Wang, Jia-qi,Gao, Hai-na,Gao, Hai-na,Hu, Han,Zheng, Nan,Wang, Jia-qi,Gao, Hai-na,Hu, Han,Zheng, Nan,Wang, Jia-qi. 2015

[17]Identification of Splice Variants, Targeted MicroRNAs and Functional Single Nucleotide Polymorphisms of the BOLA-DQA2 Gene in Dairy Cattle. Hou, Qinlei,Huang, Jinming,Ju, Zhihua,Li, Qiuling,Li, Liming,Wang, Changfa,Sun, Tao,Wang, Lingling,Hou, Minghai,Zhong, Jifeng,Hang, Suqin.

[18]Maturation of dendritic cells in vitro and immunological enhancement of mice in vivo by pachyman- and/or OVA-encapsulated poly(D, L-lactic acid) nanospheres. Zheng, Sisi,Luo, Li,Liu, Zhenguang,Bo, Ruonan,Hu, Yuanliang,Liu, Jiaguo,Wang, Deyun,Qin, Tao,Huang, Yifan,Wang, Deyun,Lu, Yu. 2018

[19]Plasmid containing CpG motifs enhances the efficacy of porcine reproductive and respiratory syndrome live attenuated vaccine. Guo, Xiaoyu,Hou, Shaohua,Zhu, Hongfei,Guo, Xiaoyu,Sanchez-Vizcaino, J. M.,Guo, Xiaoyu,Sanchez-Vizcaino, J. M.,Zhang, Quan,Zhai, Guoqin. 2011

[20]A genome-wide association study identifies major loci affecting the immune response against infectious bronchitis virus in chicken. Luo, Chenglong,Qu, Hao,Ma, Jie,Wang, Jie,Shu, Dingming,Hu, Xiaoxiang,Li, Ning,Luo, Chenglong,Qu, Hao,Ma, Jie,Wang, Jie,Shu, Dingming. 2014

作者其他论文 更多>>