Physiological responses and gene expression changes in the western mosquitofish (Gambusia affinis) exposed to progesterone at environmentally relevant concentrations
文献类型: 外文期刊
第一作者: Hou, Liping
作者: Hou, Liping;Yang, Yang;Shu, Hu;Cheng, Xuemei;Xu, Hongyan;Ying, Guangguo;Zhao, Jianliang;Ying, Guangguo;Zhao, Jianliang
作者机构:
关键词: Progesterone;Fish;Masculinization;Endocrine disruption;Histopathology;Gene expression
期刊名称:AQUATIC TOXICOLOGY ( 影响因子:4.964; 五年影响因子:5.071 )
ISSN: 0166-445X
年卷期: 2017 年 192 卷
页码:
收录情况: SCI
摘要: Progesterone (P4) is a natural and synthetic steroid, widely distributed in the aquatic environments. It can lead to adverse effects on the endocrine system in aquatic organisms. This study investigated the toxicological effects of exposure to environmentally relevant concentrations (4, 44, and 410 ng/L) of progesterone for 42 d on adult female mosquitofish, Gambusia affinis. We performed morphological and histological analyses on gonads, anal fins, liver, and gills after the exposure of mosquito fish to P4. The expression levels of genes (vtg, er, and ar isoforms) related to fish reproduction and detoxification (cyp1a) in the liver were quantified by quantitative real-time polymerase chain reaction. The results showed that the progesterone exposure induced slight masculinization in female mosquitofish, influenced the oocyte maturation as revealed by histology of the ovaries, and caused severe damages to the liver and gills of adult female mosquitofish. It also suppressed the mRNAs expression of vtg, er, cyp1a, and significantly enhanced the expression of ar mRNA in the liver. This study reveals the molecular and physiological effects of progesterone at environmentally relevant concentrations, which might further be translated to alterations in the reproduction of mosquitofish.
分类号:
- 相关文献
作者其他论文 更多>>
-
Arbuscular mycorrhizal fungi enhance drought resistance and alter microbial communities in maize rhizosphere soil
作者:Li, Juan;Chen, Guo;Yao, Mengyao;Liu, Zhigang;Li, Xiaorong;Yang, Yang;Cai, Darun;Tuerxun, Zumuremu;Li, Bo;Nie, Tengkun;Chen, Xunji;Zhou, Liuyan;Yang, Xinping
关键词:Maize seedling; AMF; Drought stress; Rhizosphere microbe; Soil function
-
Natural acidic deep eutectic solvent-mediated microwave-assisted simultaneous hydrodistillation, hydrolysis, and extraction for obtaining essential oils, gallic acid and ellagic acid from Liquidambar formosana leaves and fruits
作者:Zhang, Ke;Gao, Hongfei;Yang, Yang;Ping, Yifan;Yang, Lei;Tian, Hao;Gu, Huiyan
关键词:Natural deep eutectic solvent; Liquidambar formosana; Essential oils; Microwave simultaneous hydrodistillation; Hydrolysis; And extraction
-
Physiological and Transcriptome Analysis Provide Insights into the Effects of Low and High Selenium on Methionine and Starch Metabolism in Rice Seedlings
作者:Yang, Yang;Zhang, Jiarui;Sun, Lijuan;Qin, Qin;Yang, Shiyan;Wang, Jun;Sun, Yafei;Xue, Yong
关键词:selenium; rice; transcriptome; physiological
-
Accelerated removal and mechanism of tetracycline from water using immobilized bacteria combined with microalgae
作者:Wang, Jinli;Chen, Xiangnan;Sun, Haibo;Li, Xueying;Lu, Qiang;Qin, Pufeng;Yang, Yang;Luo, Lin;Yang, Yuan;Wu, Zhibin;Wang, Jinli;Chen, Xiangnan;Sun, Haibo;Li, Xueying;Lu, Qiang;Qin, Pufeng;Yang, Yang;Luo, Lin;Yang, Yuan;Wu, Zhibin;Wang, Jinli;Chen, Xiangnan;Li, Xueying;Lu, Qiang;Qin, Pufeng;Yang, Yang;Luo, Lin;Yang, Yuan;Wu, Zhibin;Lai, Dengni;Peng, Xin
关键词:Tetracycline; Alcaligenes faecalis; Microalgae; Wastewater treatment; Mechanisms of removal
-
Picoxystrobin causes mitochondrial dysfunction in earthworms by interfering with complex enzyme activity and binding to the electron carrier cytochrome c protein
作者:Zhao, Wentian;Jiang, Jiazhen;Wang, Chengju;Wang, Kai;Mu, Xiyan;Yang, Yang
关键词:Picoxystrobin; Earthworm; Mitochondrial dysfunction; Environmental level; Molecular docking
-
MtCro: multi-task deep learning framework improves multi-trait genomic prediction of crops
作者:Chao, Dian;Wan, Fengqiang;Yang, Yang;Wang, Hao;Yan, Shen;Fang, Wei
关键词:Deep learning; Genomic prediction; Multi-task learning; Crop breeding
-
Foisc1 regulates growth, conidiation, sensitivity to salicylic acid, and pathogenicity of Fusarium oxysporum f. sp. cubense tropical race 4
作者:Guo, Lijia;Wang, Jun;Zhou, You;Liang, Changcong;Liu, Lei;Yang, Yang;Huang, Junsheng;Yang, Laying;Guo, Lijia;Wang, Jun;Zhou, You;Liang, Changcong;Liu, Lei;Yang, Yang;Huang, Junsheng;Yang, Laying;Guo, Lijia;Wang, Jun;Zhou, You;Liang, Changcong;Liu, Lei;Yang, Yang;Huang, Junsheng;Yang, Laying;Guo, Lijia;Wang, Jun;Zhou, You;Liang, Changcong;Liu, Lei;Yang, Yang;Huang, Junsheng;Yang, Laying
关键词:Vascular wilt of banana; Isochorismatase; Pathogenicity; Salicylic acid; Defense response; Fusaric acid biosynthesis