The modulation effect of lotus (Nelumbo nucifera Gaertn.) seeds oligosaccharides with different structures on intestinal flora and action mode of growth effects on Bifidobacterium in vivo and in vitro

文献类型： 外文期刊

第一作者： Ma, Xiaoqing

作者： Ma, Xiaoqing;Zheng, Zhichang;Zuo, Jiaxin;Ju, Jianing;Zheng, Baodong;Lu, Xu;Wang, Qi;Zheng, Baodong;Lu, Xu;Ma, Xiaoqing;Zheng, Zhichang;Wang, Qi;Zuo, Jiaxin;Lu, Xu;Lu, Xu

作者机构：

关键词： Lotus seed; Oligosaccharides; Fecal gut microbiota; Prebiotics; Bifidobacterium; In vitro fermentation; Structures; Structure activity relationship

期刊名称：FOOD CHEMISTRY （ 影响因子：8.8； 五年影响因子：8.6 ）

ISSN： 0308-8146

年卷期： 2023 年 419 卷

页码：

收录情况： SCI

摘要： Natural lotus seed oligosaccharides monomers (LOSs: LOS3-1, LOS3-2, and LOS4) were prepared by preparative chromatography and were hydroxyl-labeled with fluorescein isothiocyanate (FITC). The prebiotic properties of LOSs by the gut microbiota of male Balb/C mice in vivo and in vitro were studied. In vivo experiment results showed that LOS4 could significantly increase the average daily food consumption, weight, liver index and the abundance of Bacteroides and Bifidobacterium for mice (p < 0.05). In addition, LOS4 also had significant pro-liferation effect on Bifidobacterium adolescentis and longum in vitro (p < 0.05). Laser confocal microscopy observation showed interaction site between LOS4-FITC and Bifidobacterium adolescentis was located outside and inside of cell, which was completed within 1 h. The relationship between structures of LOSs and prebiotics of intestinal flora (especially Bifidobacterium), and expanded the knowledge on the effects of carbohydrate poly-merization degree (DP) and glycosidic bond connection with fermentation selectivity of bacteria was studied.

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