Risk of Environmental Exposure to H7N9 Influenza Virus via Airborne and Surface Routes in a Live Poultry Market in Hebei, China

文献类型： 外文期刊

第一作者： Zhang, Cheng

作者： Zhang, Cheng;Guo, Kangkang;Chen, Ligong;Wang, Xuejing;Liu, Juxiang;Dong, Shishan;Zhang, Cheng;Guo, Kangkang;Cui, Huan;Zhang, Chunmao;Guo, Zhendong;Cui, Huan;Li, Jiaming;Fu, Yingying;Wang, Zhongyi

作者机构：

关键词： pathogenicity; environmental and airborne transmissibility; mammalian adaption; human exposure risk

期刊名称：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY （ 影响因子：5.293； 五年影响因子：5.882 ）

ISSN： 2235-2988

年卷期： 2021 年 11 卷

页码：

收录情况： SCI

摘要： Environmental transmission of viruses to humans has become an early warning for potential epidemic outbreaks, such as SARS-CoV-2 and influenza virus outbreaks. Recently, an H7N9 virus, A/environment/Hebei/621/2019 (H7N9), was isolated by environmental swabs from a live poultry market in Hebei, China. We found that this isolate could be transmitted by direct contact and aerosol in mammals. More importantly, after 5 passages in mice, the virus acquired two adaptive mutations, PB1-H115Q and B2-E627K, exhibiting increased virulence and aerosol transmissibility. These results suggest that this H7N9 virus might potentially be transmitted between humans through environmental or airborne routes.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序