Simultaneous Identification and Detection of 23 Perfluorinated Alkyl Substances in Processed Aquatic Products by Impurity Delay Using Liquid Chromatography Coupled with Quadrupole/Linear Ion Trap Mass Spectrometry

文献类型： 外文期刊

第一作者： Guo Meng-Meng

作者： Guo Meng-Meng;Wu Hai-Yan;Lu Li-Na;Tan Zhi-Jun;Zhai Yu-Xiu;Zhao Chun-Xia;Fu Shu-Lin;Li Zhao-Xin;Guo Meng-Meng;Wu Hai-Yan;Lu Li-Na;Tan Zhi-Jun;Zhai Yu-Xiu;Zhao Chun-Xia;Fu Shu-Lin;Li Zhao-Xin

作者机构：

关键词： Perfluorinated alkyl substances;Processed aquatic products;Impurity delay;Liquid chromatography-quadrupole/linear ion trap tandem mass spectrometry

期刊名称：CHINESE JOURNAL OF ANALYTICAL CHEMISTRY （ 影响因子：1.134； 五年影响因子：0.909 ）

ISSN： 0253-3820

年卷期： 2015 年 43 卷 8 期

页码：

收录情况： SCI

摘要： A comprehensive method for the simultaneous identification and detection of 23 perfluorinated alkyl substances (PFASs) in processed aquatic products by impurity delay was developed using liquid chromatography coupled with quadrupole/linear ion trap tandem mass spectrometry (LC-Q/Trap-MS). The sample was extracted with acidified acetonitrile, cleaned. up by dispersive solid phase extraction using C-18 and graphitized carbon blacks (GCB). The separation of 23 PFASs was performed on a Kinetex XB-C-18 (100 mmx 2.1 mm, 2.6 mu m) column using gradient elution of 5 mmol/L ammonium acetate and methanol as mobile phase. And a short C-18 HPLC column was inserted between the mixer and the autosample, which delayed compounds coming from the LC system. A scheduled multiple reaction monitoring (MRM) in negative mode as survey scan and an enhanced product ion (EPI) scan as dependent scan in an information. dependent acquisition (IDA) experiment were adopted in mass spectrometry acquisition. On. line lab. built MS/MS library and the isotope internal standards were employed for the identification and quantification. The calibration curves for the detection of 23 PFASs were linear well with correlation coefficient over 0.995. The limits of quantification for all analytes were ranged from 0.02 mu g/kg to 0.1 mu g/kg. The average spiked recoveries for 23 PFASs were between 67.5% and 116.4%, with relative standard deviations (RSDs) from 5.2% to 14.7%. The background coming from the part of LC was controlled well by the impurity delay. The proposed method can be used to identify and detect the 23 PFASs in a single run, and also suitable for the analysis of processed aquatic product samples.

分类号：

  • 相关文献

[1]Determination of 23 Perfluorinated Alkyl Substances in Fishery Products by Ultra Fast Liquid Chromatography-Tandem Mass Spectrometry. Guo Meng-Meng,Wu Hai-Yan,Li Zhao-Xin,Tan Zhi-Jun,Zhai Yu-Xiu,Guo Meng-Meng,Wu Hai-Yan,Li Zhao-Xin,Tan Zhi-Jun,Zhai Yu-Xiu. 2013

作者其他论文 更多>>

微信小程序