Gut microbiota changes in horses with Chlamydia

文献类型： 外文期刊

第一作者： Jin, Youshun

作者： Jin, Youshun;Li, Wei;Ba, Xuli;Wang, Yanyan;Li, Zhaocai;Zhou, Jizhang;Jin, Youshun;Ba, Xuli;Zhou, Jizhang;Li, Yunhui;Zhang, Huaiyu

作者机构：

关键词： Zoonoses; Chlamydia; Horse; Gut microbiota

期刊名称：BMC MICROBIOLOGY （ 影响因子：4.2； 五年影响因子：4.7 ）

ISSN： 1471-2180

年卷期： 2023 年 23 卷 1 期

页码：

收录情况： SCI

摘要： Background Zoonotic diseases pose a significant threat to public health. Chlamydia, as an intracellular pathogen, can colonize the intestinal tract of humans and animals, changing the gut microbiota. However, only a few studies have evaluated alterations in the gut microbiota of horses infected with Chlamydia. Therefore, this study aimed to investigate gut microbiota and serum biochemical indicators in horses with Chlamydial infection (IG) and healthy horses (HG). Fecal and blood samples were collected from 16 horses (IG: 10; HG: 6) before morning feeding for the determination of gut microbiota and serum biochemical parameters.Results The results showed that total globulin (GLB), alanine aminotransferase (ALT), and creatine kinase (CK) levels were significantly increased in IG compared with HG. Notably, the gut microbial diversity increased in IG compared with HG. Furthermore, Moraxellaceae and Akkermanisa abundance decreased in IG, while Streptococcus, Treponema, Prevotella, and Paraprevotella abundances (13 genera of bacterial species) increased. Compared with HG, carbohydrate metabolism increased in IG while amino acid metabolism decreased. In addition, the abundance of 18 genera of bacteria was associated with the level of five serum biochemical indicators.Conclusions In summary, this study elucidated the influence of Chlamydia infection in horses on the gut microbiota, unraveling consequential alterations in its composition and metabolic profile. Therefore, this study improves the understanding of Chlamydia-induced intestinal infections.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序