文献类型： 外文期刊
第一作者： Yin, Chang
作者： Yin, Chang;Zhong, Ruqing;Zhang, Weidong;Liu, Lei;Chen, Liang;Zhang, Hongfu
作者机构：
关键词： bile acid metabolism; gut microbiota; enterohepatic circulation; dysbiosis; metabolic disorders; diagnostic biomarker
期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：5.6； 五年影响因子：6.2 ）
ISSN： 1661-6596
年卷期： 2023 年 24 卷 15 期
页码：
收录情况： SCI
摘要： Bile acids (BAs) are well known to facilitate the absorption of dietary fat and fat-soluble molecules. These unique steroids also function by binding to the ubiquitous cell membranes and nuclear receptors. As chemical signals in gut-liver axis, the presence of metabolic disorders such as nonalcoholic fatty liver disease (NAFLD), type 2 diabetes mellitus (T2DM), and even tumors have been reported to be closely related to abnormal levels of BAs in the blood and fecal metabolites of patients. Thus, the gut microbiota interacting with BAs and altering BA metabolism are critical in the pathogenesis of numerous chronic diseases. This review intends to summarize the mechanistic links between metabolic disorders and BAs in gut-liver axis, and such stage-specific BA perturbation patterns may provide clues for developing new auxiliary diagnostic means.
分类号：
- 相关文献
作者其他论文 更多>>
-
Probiotics encapsulated by calcium pectin/chitosan-calcium pectin/sodium alginate-pectin-whey through biofilm-based microencapsulation strategy and their preventive effects on ulcerative colitis
作者：Rao, Yu;Deng, Jia;Zhang, Chengyi;Song, Yunlong;Liu, Lei
关键词：Biofilm-based probiotics microencapsulation; Microencapsulate characteristics; Tolerance properties; Ulcerative colitis; Gut microbiota
-
Effects of different energy levels in low-protein diet on liver lipid metabolism in the late-phase laying hens through the gut-liver axis
作者：Hu, Hong;Huang, Ying;Li, Anjian;Mi, Qianhui;Pan, Hongbin;Wang, Kunping;Bai, Xi;Chen, Liang;Zhao, Zelong;Zhang, Qiang
关键词：Cecal microbiome; Energy/protein imbalance; Late-phase laying hens laying hens; Liver lipid metabolism; Low-protein diet; Multi-omics
-
Maize actin depolymerizing factor 1 ( ZmADF1 ) negatively regulates pollen development
作者：Lv, Guihua;Wu, Zhengxin;Li, Xiangnan;Wang, Tingzheng;Chen, Jianjian;Liu, Lei;Zhang, Yuanyuan;Li, Yunfeng;Zhang, Yahui;Ren, Wenchuang
关键词：Actin depolymerizing factor 1; Overexpression; Gene editing; Maize; Pollen development
-
The Effect of Irradiation Combined with Sodium Hydroxide Pretreatment on Component, Structure, Utilization Efficiency of Phragmites Australis
作者：Qi, Hui;Wu, Xiaofen;Chen, Liang;Liu, An;Deng, Ming;Wei, Dongning;Wang, Keqin;Wang, Danyang;Peng, Zhili
关键词：Phragmites australis; Irradiation combined with NaOH pretreatment; Component; Structure; Utilization efficiency
-
Integrated Multi-Omics Analysis to Reveal the Molecular Mechanisms of Inflorescence Elongation in Medicago sativa
作者：Huang, Xiuzheng;Liu, Lei;Qiang, Xiaojing;Meng, Yuanfa;Li, Zhiyong;Huang, Fan
关键词：alfalfa; inflorescence elongation; multi-omics; functional genes
-
Rhein: A potent immunomodulator empowering largemouth bass against MSRV infection
作者：Zhang, Xu;Liu, Lei;Wang, Huan;Qiu, Tianxiu;Zhou, Yan;Shan, Lipeng;Wang, Zixuan;Hu, Yang;Chen, Jiong;Zhang, Xu;Liu, Lei;Wang, Huan;Qiu, Tianxiu;Zhou, Yan;Shan, Lipeng;Wang, Zixuan;Hu, Yang;Chen, Jiong;Xue, Mingyang;Liu, Guanglu
关键词：Rhein; Immunomodulator; Largemouth bass; Apoptosis; Micropterus salmoides rhabdovirus; Antiviral
-
Effects of the compound extracts of Caprifoliaceae and Scutellaria baicalensis Georgi on the intestinal microbiota and antioxidant function
作者：Zhang, Shunfen;Tang, Shanlong;Zhong, Ruqing;Chen, Liang;Zhang, Hongfu;Zhang, Shunfen;Lv, Huiyuan;Lv, Huiyuan;Cai, Xueying
关键词：Scutellaria baicalensis Georgi; Caprifoliaceae; gut microbe; antioxidant; inflammatory
