Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review

文献类型： 外文期刊

第一作者： Meng, Xiao

作者： Meng, Xiao;Li, Hua-Bin;Zhou, Jing;Gan, Ren-You

作者机构：

关键词： resveratrol; bioactivities; anticancer; anti-obesity; antidiabetes; molecular mechanisms

期刊名称：FOODS （ 影响因子：4.35； 五年影响因子：4.957 ）

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年卷期： 2020 年 9 卷 3 期

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收录情况： SCI

摘要： Resveratrol is a bioactive compound in many foods. Since its anticancer activity was reported in 1997, its health benefits have been intensively investigated. Resveratrol has antioxidant, anti-inflammatory, immunomodulatory, glucose and lipid regulatory, neuroprotective, and cardiovascular protective effects, therefore, can protect against diverse chronic diseases, such as cardiovascular diseases (CVDs), cancer, liver diseases, obesity, diabetes, Alzheimer's disease, and Parkinson's disease. This review summarizes the main findings of resveratrol-related health benefits in recent epidemiological surveys, experimental studies, and clinical trials, highlighting its related molecular mechanisms. Resveratrol, therefore, has been regarded as a potent candidate for the development of nutraceuticals and pharmaceuticals to prevent and treat certain chronic diseases.

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