Anti-phytopathogenic Bacterial Metabolites From the Seaweed-Derived Fungus Aspergillus sp. D40

文献类型: 外文期刊

第一作者: Huang, Rui-Huan

作者: Huang, Rui-Huan;Zhang, Peng;Wang, Dan;Li, Yi-Qiang;Zhao, Dong-Lin;Wang, Xiao-Qiang;Zhang, Cheng-Sheng;Lin, Wei;Liu, Jian-Yang;Wang, Dan;Li, Wei

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关键词: furanones; penicillic acid; Ralstonia solanacearum; phytopathogenic bacteria; antibacterial activity

期刊名称:FRONTIERS IN MARINE SCIENCE ( 影响因子:4.912; 五年影响因子:5.125 )

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年卷期: 2020 年 7 卷

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收录情况: SCI

摘要: In order to search for new lead compounds with anti-phytopathogenic bacterial activity, three pairs of new furanone derivatives, sclerotiorumins D-F (1-3), and eight known compounds (4-11) were isolated from the seaweed-derived fungus, Aspergillus sp. D40, fermented with potato dextrose seawater (PDW) medium. Their structures were determined using comprehensive spectroscopic analyzes including HRESIMS, 1D and 2D NMR data. Compounds 1-4 and 9 existed as inseparable mixtures of a pair of epimers. Penicillic acid (7) exhibited clear antibacterial activity against Ralstonia solanacearum and several other plant pathogenic bacteria with IC50 values ranging from 11.6 to 58.2 mu g/mL.

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