Regioselective aromatic O-demethylation with an artificial P450BM3 peroxygenase system

文献类型: 外文期刊

第一作者: Jiang, Yihui

作者: Jiang, Yihui;Wang, Chunlan;Wang, Fang;Xu, Jiakun;Jiang, Yihui;Ma, Nana;Chen, Jie;Liu, Chuanfei;Cong, Zhiqi;Ma, Nana;Chen, Jie;Liu, Chuanfei;Cong, Zhiqi;Ma, Nana;Chen, Jie;Cong, Zhiqi

作者机构:

期刊名称:CATALYSIS SCIENCE & TECHNOLOGY ( 影响因子:6.119; 五年影响因子:6.339 )

ISSN: 2044-4753

年卷期: 2020 年 10 卷 5 期

页码:

收录情况: SCI

摘要: Several simple single- and double-mutants of cytochrome P450BM3 enzymes enabled a highly regioselective O-demethylation of aromatic ethers with H2O2 with the assistance of a dual-functional small molecule (DFSM). The DFSM-facilitated P450BM3 peroxygenase system provides an alternative, simple approach for a key step in the bioconversion of lignin compared with reported NADPH-dependent P450 monooxygenases.

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